Protein Alignment sna and CRZ1

DIOPT Version :10

• Sequence 1: NP_476732.1
• Gene: sna / 34908
• FlyBaseID: FBgn0003448
• Length: 390
• Species: Drosophila melanogaster
• Sequence 2: NP_014371.1
• Gene: CRZ1 / 855704
• SGDID: S000004972
• Length: 678
• Species: Saccharomyces cerevisiae
• Alignment Length: 506
• Identity: 99/506 - (19%)
• Similarity: 156/506 - (30%)
• Gaps: 187/506 - (36%)

  Fly    33 DSQFAQDQ---------PQDL-------SLKRGRDE---------ETQDYQQPEPKRDY--VLNL 70
            ||.::..:         ||||       .|....|:         ...:|..|.....|  :.||
Yeast   190 DSNYSDTESNYHTPYLYPQDLVSSPAMSHLTANNDDFDDLLSVASMNSNYLLPVNSHGYKHISNL 254

  Fly    71 SKTPERNSSSSSNSCLLSPPVEAQDYLPTEIHMRGL--TAGTTGYTTATPTTINPFQSAFVMAAG 133
            .:..:..|.:.|::.|||    |.:.........|:  ||.|...|.|    ||..:      .|
Yeast   255 DELDDLLSLTYSDNNLLS----ASNNSDFNNSNNGIINTADTQNSTIA----INKSK------VG 305

  Fly   134 CN-------PISALWSSYQPHLAAFPSPASSMASPQSVYSYQQMTPPSSPGSDLETGS------- 184
            .|       |.|:.           |||::..|....:.|.|:......|..:.:.|:
Yeast   306 TNQKMLLTIPTSST-----------PSPSTHAAPVTPIISIQEFNEGHFPVKNEDDGTLQLKVRD 359

  Fly   185 -------------EPEDLSVRNDIPLPALFHLFDE------AKSSSSGASVSSSSGYSYTPAMSA 230
                         .|:|....|: .|..:...|::      .|...|....|.:|..|:|...|:
Yeast   360 NESYSATNNNNLLRPDDNDYNNE-ALSDIDRSFEDIINGRKLKLKKSRRRSSQTSNNSFTSRRSS 423

  Fly   231 SS---------ASVAANHAK--------------------------------------------- 241
            .|         .|::||..|
Yeast   424 RSRSISPDEKAKSISANREKLLEMADLLPSSENDNNRERYDNDSKTSYNTINSSNFNEDNNNNNL 488

  Fly   242 ------------NYRFKCDECQKMYSTSMGLSKHRQFHCPAAECNQE------------KKTHSC 282
                        |.:.:.|:..|.....:.:....||.......|.:            ||..:.
Yeast   489 LTSKPKIESGIVNIKNELDDTSKDLGILLDIDSLGQFEQKVGFKNDDNHENNDNGTFSVKKNDNL 553

  Fly   283 EECGKLYTTIGALKMHIRTHTLPCKCPICGKAFSRPWLLQGHIRTHTGEKPFQCPDCPRSFADRS 347
            |:...:...        |.:.....|.:|||.|:||:.|:.|:||||.|:||.|..|.::||.:.
Yeast   554 EKLDSVTNN--------RKNPANFACDVCGKKFTRPYNLKSHLRTHTNERPFICSICGKAFARQH 610

  Fly   348 NLRAHQQTHVDVKKYAC---------QVCHKSFSRMSLLNKH----SSSNC 385
            :.:.|:..|...|:|.|         ..|.|.|:|...|.:|    |...|
Yeast   611 DRKRHEDLHTGKKRYVCGGKLKDGKPWGCGKKFARSDALGRHFKTESGRRC 661

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sna	NP_476732.1	SFP1	<245..303	CDD:227516	9/69 (13%)
		C2H2 Zn finger	247..267	CDD:275368	3/19 (16%)
		C2H2 Zn finger	282..302	CDD:275368	2/19 (11%)
		zf-C2H2	306..328	CDD:395048	10/21 (48%)
		C2H2 Zn finger	308..328	CDD:275368	10/19 (53%)
		zf-H2C2_2	321..344	CDD:463886	11/22 (50%)
		zf-C2H2	334..356	CDD:395048	6/21 (29%)
		C2H2 Zn finger	336..356	CDD:275368	5/19 (26%)
		zf-H2C2_2	348..373	CDD:463886	8/33 (24%)
		C2H2 Zn finger	364..380	CDD:275368	6/24 (25%)
CRZ1	NP_014371.1	COG5048	139..617	CDD:227381	87/460 (19%)
		C2H2 Zn finger	571..591	CDD:275368	10/19 (53%)
		Zn_ribbon_recom	598..656	CDD:433183	15/57 (26%)
		C2H2 Zn finger	599..619	CDD:275368	5/19 (26%)
		C2H2 Zn finger	627..655	CDD:275368	7/27 (26%)