DRSC/TRiP Functional Genomics Resources

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Protein Alignment sna and SCRT2

DIOPT Version :9

Sequence 1:NP_476732.1 Gene:sna / 34908 FlyBaseID:FBgn0003448 Length:390 Species:Drosophila melanogaster
Sequence 2:NP_149120.1 Gene:SCRT2 / 85508 HGNCID:15952 Length:307 Species:Homo sapiens


Alignment Length:275 Identity:100/275 - (36%)
Similarity:136/275 - (49%) Gaps:16/275 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly   120 TINPFQSAFVMAAGCNPISALWSSYQPH------LAAFPSPASSMASPQSVY---SYQQMTPPSS 175
            |.:|.::|:|:.....|...  :.|.||      ..|...|...:|..:..|   :.::.:.|.|
Human    24 TYHPLETAYVLPGARGPPGD--NGYAPHRLPPSSYDADQKPGLELAPAEPAYPPAAPEEYSDPES 86

  Fly   176 PGSDLETGSEPEDLSVRNDIPLPALFHLFDEAKSSSSGASVSSSSGYSYTPAMSASSASVAANHA 240
            |.|.|.......:.:|.:...:.|.| :.|.......|.....:.|..........:....|...
Human    87 PQSSLSARYFRGEAAVTDSYSMDAFF-ISDGRSRRRRGGGGGDAGGSGDAGGAGGRAGRAGAQAG 150

  Fly   241 KNYRFKCDECQKMYSTSMGLSKHRQFHCPAAECNQEKKTHSCEECGKLYTTIGALKMHIRTHTLP 305
            ..:|..|.||.|.|:||..||:|:|.|    .....:....|..|||.|.::.||.||:.||.|.
Human   151 GGHRHACAECGKTYATSSNLSRHKQTH----RSLDSQLARKCPTCGKAYVSMPALAMHLLTHNLR 211

  Fly   306 CKCPICGKAFSRPWLLQGHIRTHTGEKPFQCPDCPRSFADRSNLRAHQQTHVDVKKYACQVCHKS 370
            .||.:||||||||||||||:|:|||||||.|..|.::||||||||||.|||...|.|.|:.|.||
Human   212 HKCGVCGKAFSRPWLLQGHMRSHTGEKPFGCAHCGKAFADRSNLRAHMQTHSAFKHYRCRQCDKS 276

  Fly   371 FSRMSLLNKHSSSNC 385
            |:..|.|:||..:.|
Human   277 FALKSYLHKHCEAAC 291

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
snaNP_476732.1 C2H2 Zn finger 308..328 CDD:275368 16/19 (84%)
zf-H2C2_2 321..344 CDD:290200 14/22 (64%)
zf-C2H2 334..356 CDD:278523 14/21 (67%)
C2H2 Zn finger 336..356 CDD:275368 13/19 (68%)
zf-H2C2_2 348..373 CDD:290200 15/24 (63%)
C2H2 Zn finger 364..380 CDD:275368 7/15 (47%)
C2H2 Zn finger 247..267 CDD:275368 11/19 (58%)
C2H2 Zn finger 282..302 CDD:275368 9/19 (47%)
zf-C2H2 306..328 CDD:278523 17/21 (81%)
COG5048 307..>356 CDD:227381 37/48 (77%)
SCRT2NP_149120.1 SNAG domain. /evidence=ECO:0000250 1..20
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 34..90 11/57 (19%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 116..148 2/31 (6%)
C2H2 Zn finger 157..177 CDD:275368 11/19 (58%)
COG5048 <210..>277 CDD:227381 45/66 (68%)
C2H2 Zn finger 214..234 CDD:275368 16/19 (84%)
zf-H2C2_2 227..250 CDD:290200 14/22 (64%)
C2H2 Zn finger 242..262 CDD:275368 13/19 (68%)
zf-H2C2_2 254..278 CDD:290200 14/23 (61%)
C2H2 Zn finger 270..286 CDD:275368 7/15 (47%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG2462
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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