DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sna and snai3

DIOPT Version :9

Sequence 1:	NP_476732.1	Gene:	sna / 34908	FlyBaseID:	FBgn0003448	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_001070853.1	Gene:	snai3 / 567724	ZFINID:	ZDB-GENE-061013-757	Length:	283	Species:	Danio rerio

Alignment Length:	333	Identity:	129/333 - (38%)
Similarity:	165/333 - (49%)	Gaps:	78/333 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 KRDYVLNLSKTPERNSSSSSNSCLLSPPVEAQDYLPTEIHMRGLTAGTTGYTTATPTTINPFQSA 127
            |.||.:..||..|...|.||||.|                                .|::|.|:.
Zfish    15 KPDYGVLDSKKHEMIHSESSNSKL--------------------------------KTLHPHQNM 47

  Fly   128 FVM------AAGCNPISALWSSYQP--HLAAFPSPASSMASPQSVYSYQQMTPPSSPGSDLETGS 184
            |.:      |...||||:  ..|.|  |      |:..:..|....:| .:..||||..|:.
Zfish    48 FPVPCYGNSAGWMNPISS--DIYMPPQH------PSLPIDDPILGLTY-PLPAPSSPLRDMR--- 100

  Fly   185 EPEDLSVRNDIPLPALFHLFDEAKSSSSGASVSSSSGYSYTPAMSASSASVAANHAKNYRFKCDE 249
                         |||..|   ..:..|...:|....:...| :|....:...| ::.:..:|.:
Zfish   101 -------------PALSML---EHTDPSSLQLSHRDLHEKVP-VSPLGLTTTGN-SQEHSDECFD 147

  Fly   250 CQKMYSTSMGLSKHRQFHC--PAAECNQEKKTHSCEECGKLYTTIGALKMHIRTHTLPCKCPICG 312
            |||.|.:...|:..||.||  |   |:   |..:|:.|.|.|.::||||||||||||||.|.:||
Zfish   148 CQKAYLSFSNLANQRQVHCQWP---CH---KYFTCKYCEKEYVSLGALKMHIRTHTLPCVCKLCG 206

  Fly   313 KAFSRPWLLQGHIRTHTGEKPFQCPDCPRSFADRSNLRAHQQTHVDVKKYACQVCHKSFSRMSLL 377
            ||||||||||||||||||||||.||.|.|:||||||||||.|||.::|||.|:.|.|:|||:|||
Zfish   207 KAFSRPWLLQGHIRTHTGEKPFTCPHCSRAFADRSNLRAHLQTHSEIKKYQCRNCFKTFSRISLL 271

  Fly   378 NKHSSSNC 385
            .||..:.|
Zfish   272 TKHEEAGC 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sna	NP_476732.1	C2H2 Zn finger	308..328	CDD:275368	17/19 (89%)
		zf-H2C2_2	321..344	CDD:290200	18/22 (82%)
		zf-C2H2	334..356	CDD:278523	16/21 (76%)
		C2H2 Zn finger	336..356	CDD:275368	15/19 (79%)
		zf-H2C2_2	348..373	CDD:290200	15/24 (63%)
		C2H2 Zn finger	364..380	CDD:275368	9/15 (60%)
		C2H2 Zn finger	247..267	CDD:275368	8/19 (42%)
		C2H2 Zn finger	282..302	CDD:275368	12/19 (63%)
		zf-C2H2	306..328	CDD:278523	18/21 (86%)
		COG5048	307..>356	CDD:227381	40/48 (83%)
snai3	NP_001070853.1	C2H2 Zn finger	176..196	CDD:275368	12/19 (63%)
		C2H2 Zn finger	202..222	CDD:275368	17/19 (89%)
		zf-H2C2_2	215..238	CDD:290200	18/22 (82%)
		zf-C2H2	228..250	CDD:278523	16/21 (76%)
		C2H2 Zn finger	230..250	CDD:275368	15/19 (79%)
		C2H2 Zn finger	258..274	CDD:275368	9/15 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2462
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24388
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	5	4.870