DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sna and snai2

DIOPT Version :9

Sequence 1:	NP_476732.1	Gene:	sna / 34908	FlyBaseID:	FBgn0003448	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_001008581.1	Gene:	snai2 / 494038	ZFINID:	ZDB-GENE-030326-6	Length:	257	Species:	Danio rerio

Alignment Length:	240	Identity:	118/240 - (49%)
Similarity:	141/240 - (58%)	Gaps:	18/240 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   148 LAAFPSPASSMASPQSVYSYQQMTPPSSPGSDLETGSEPEDLSVRNDIPLPALFHLFDEAKSSSS 212
            |.|.|.|........|..:|..:|..::  |:|.....|.|||..:..|            ||.|
Zfish    34 LKALPVPVIPQPEVLSPVAYNPITVWTT--SNLPLSPLPHDLSPISGYP------------SSLS 84

  Fly   213 GASVSSSSGYSYTPAMSASSASVAANHAKNYRFKCDECQKMYSTSMGLSKHRQFHCPAAECNQEK 277
            ..|.:.....|.:|.........:...:...:|:|..|.|.|||..||.||:|.||.|    |.:
Zfish    85 DTSSNKDHSGSESPRSDEDERIQSTKLSDAEKFQCGLCNKSYSTYSGLMKHKQLHCDA----QSR 145

  Fly   278 KTHSCEECGKLYTTIGALKMHIRTHTLPCKCPICGKAFSRPWLLQGHIRTHTGEKPFQCPDCPRS 342
            |:.||:.|.|.|.::||||||||||||||.|.:||||||||||||||||||||||||.||.|.|:
Zfish   146 KSFSCKYCEKEYVSLGALKMHIRTHTLPCVCKMCGKAFSRPWLLQGHIRTHTGEKPFSCPHCSRA 210

  Fly   343 FADRSNLRAHQQTHVDVKKYACQVCHKSFSRMSLLNKHSSSNCTI 387
            ||||||||||.|||.|||||.|:.|.|:|||||||:||..|.|.|
Zfish   211 FADRSNLRAHLQTHSDVKKYQCKNCSKTFSRMSLLHKHEESGCCI 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sna	NP_476732.1	C2H2 Zn finger	308..328	CDD:275368	17/19 (89%)
		zf-H2C2_2	321..344	CDD:290200	18/22 (82%)
		zf-C2H2	334..356	CDD:278523	16/21 (76%)
		C2H2 Zn finger	336..356	CDD:275368	15/19 (79%)
		zf-H2C2_2	348..373	CDD:290200	17/24 (71%)
		C2H2 Zn finger	364..380	CDD:275368	10/15 (67%)
		C2H2 Zn finger	247..267	CDD:275368	11/19 (58%)
		C2H2 Zn finger	282..302	CDD:275368	12/19 (63%)
		zf-C2H2	306..328	CDD:278523	18/21 (86%)
		COG5048	307..>356	CDD:227381	40/48 (83%)
snai2	NP_001008581.1	C2H2 Zn finger	119..139	CDD:275368	11/19 (58%)
		C2H2 Zn finger	150..170	CDD:275368	12/19 (63%)
		C2H2 Zn finger	176..196	CDD:275368	17/19 (89%)
		zf-H2C2_2	189..212	CDD:290200	18/22 (82%)
		C2H2 Zn finger	204..224	CDD:275368	15/19 (79%)
		zf-H2C2_2	216..241	CDD:290200	17/24 (71%)
		C2H2 Zn finger	232..248	CDD:275368	10/15 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2462
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	221	1.000	Inparanoid score	I3523
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004977
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR24388
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	7	6.920