DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sna and sqz

DIOPT Version :9

Sequence 1:	NP_476732.1	Gene:	sna / 34908	FlyBaseID:	FBgn0003448	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_524403.1	Gene:	sqz / 42300	FlyBaseID:	FBgn0010768	Length:	535	Species:	Drosophila melanogaster

Alignment Length:	368	Identity:	95/368 - (25%)
Similarity:	132/368 - (35%)	Gaps:	140/368 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 SQFAQDQPQ--DLSLKRGRDEETQDY---QQPEPKRDYVLNLSKTPERN-------SSSSSNSCL 86
            |:|.|:..:  |.|||.|..:..|..   |||.|.:....:|....::.       |.|:.|
  Fly    45 SEFRQNVAERLDYSLKNGLVQHQQQMVMEQQPHPDQQQQQHLHHPQQQQHPPQLKVSYSAPN--- 106

  Fly    87 LSPPV--EAQDYLPTEIHMRGLTAGTTGYTTATPTTINPFQSAFVMAAGCNPISALWSSYQPHLA 149
             |||.  |.|:                                              ..|.|:
  Fly   107 -SPPTPHEQQE----------------------------------------------QKYDPN-- 122

  Fly   150 AFPSPASSMASPQSVYSYQQMTPPSSPGSDLETGSEPEDLSVRNDIPLPALFHLFDEAKSSSSGA 214
                     .||..    |||:..|..||:   ||.||:.|.|.|         .|:||.
  Fly   123 ---------RSPPR----QQMSSASGSGSN---GSSPEEESRRGD---------GDQAKP----- 157

  Fly   215 SVSSSSGYSYTPAMSASSASVAANHAKNYRFKCDECQKMYSTSMGLSKHRQFHCPAAECNQEKKT 279
                                          :||..|.|.::.|..||:|.:.|...       |.
  Fly   158 ------------------------------YKCGSCSKSFANSSYLSQHTRIHLGI-------KP 185

  Fly   280 HSCEECGKLYTTIGALKMHIRTHT--LPCKC--PICGKAFSRPWLLQGHIRTHTGEKPFQCPDCP 340
            :.||.|.:.:|.:..|:.||||||  .|.||  ..|.||||:...||.|.|.|..:|||:|..|.
  Fly   186 YRCEICQRKFTQLSHLQQHIRTHTGDKPYKCRHAGCPKAFSQLSNLQSHSRCHQTDKPFKCNSCY 250

  Fly   341 RSFADRSNLRAHQQTHVD---VKKYACQVCHKSFSRMSLLNKH 380
            :.|:|...|..|...|.|   :|.:.|.:|.||:::.:.|.||
  Fly   251 KCFSDEMTLLEHIPKHKDSKHLKTHICNLCGKSYTQETYLQKH 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sna	NP_476732.1	C2H2 Zn finger	308..328	CDD:275368	10/21 (48%)
		zf-H2C2_2	321..344	CDD:290200	10/22 (45%)
		zf-C2H2	334..356	CDD:278523	7/21 (33%)
		C2H2 Zn finger	336..356	CDD:275368	6/19 (32%)
		zf-H2C2_2	348..373	CDD:290200	9/27 (33%)
		C2H2 Zn finger	364..380	CDD:275368	5/15 (33%)
		C2H2 Zn finger	247..267	CDD:275368	7/19 (37%)
		C2H2 Zn finger	282..302	CDD:275368	8/19 (42%)
		zf-C2H2	306..328	CDD:278523	11/23 (48%)
		COG5048	307..>356	CDD:227381	21/50 (42%)
sqz	NP_524403.1	C2H2 Zn finger	160..180	CDD:275368	7/19 (37%)
		zf-H2C2_2	172..197	CDD:290200	8/31 (26%)
		zf-C2H2	186..208	CDD:278523	8/21 (38%)
		C2H2 Zn finger	188..208	CDD:275368	8/19 (42%)
		zf-C2H2_8	191..271	CDD:292531	33/79 (42%)
		zf-H2C2_2	200..227	CDD:290200	14/26 (54%)
		C2H2 Zn finger	216..238	CDD:275368	10/21 (48%)
		C2H2 Zn finger	246..266	CDD:275368	6/19 (32%)
		C2H2 Zn finger	277..297	CDD:275368	7/17 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457133
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930