DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sna and CG4820

DIOPT Version :9

Sequence 1:	NP_476732.1	Gene:	sna / 34908	FlyBaseID:	FBgn0003448	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_001097748.1	Gene:	CG4820 / 41344	FlyBaseID:	FBgn0037876	Length:	362	Species:	Drosophila melanogaster

Alignment Length:	229	Identity:	54/229 - (23%)
Similarity:	80/229 - (34%)	Gaps:	61/229 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   161 PQSVYSYQQMTPP----SSPGSDLETGSEPEDLSVRNDIPLPALFHLFDEAKSSSSGASVSSSSG 221
            ||:.|...|:...    ::||.|:              :|||.     |..::.:..|:.::.
  Fly   129 PQAPYPENQLEQALSYGNAPGEDI--------------LPLPE-----DYGEAQTEVATTTNE-- 172

  Fly   222 YSYTPAMSASSASVAANHAKNYRFKCDECQKMYSTSMGLSKHRQFHCPAAECNQEKKTHSCEECG 286
                ||...|.     |.||   .|    .|.::..:|   .:..|....:..|.|:.  .:..|
  Fly   173 ----PAQRRSK-----NTAK---IK----SKKHTMRVG---RKLIHVKVIDDKQPKRI--VDRNG 216

  Fly   287 KLYTTIGALKMHIRTHTLPCKCPICGKAFSRPWLLQGHIRTHTGEKPFQCPDCPRSFADRSNLRA 351
                          ....||.|..||:.|.....|..|:..|||.|||:|..|.:.......||.
  Fly   217 --------------PSAKPCICEHCGRQFKDTSNLHVHLLRHTGTKPFECDQCHQKCYTLHLLRR 267

  Fly   352 HQQTHVDVKKYACQVCHKSFSRMSLLNKHSSSNC 385
            ||..|.: ..|||..|...:|..|...:|....|
  Fly   268 HQLKHTE-GPYACTFCGLEYSTNSSRVRHEREAC 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sna	NP_476732.1	C2H2 Zn finger	308..328	CDD:275368	6/19 (32%)
		zf-H2C2_2	321..344	CDD:290200	10/22 (45%)
		zf-C2H2	334..356	CDD:278523	7/21 (33%)
		C2H2 Zn finger	336..356	CDD:275368	6/19 (32%)
		zf-H2C2_2	348..373	CDD:290200	9/24 (38%)
		C2H2 Zn finger	364..380	CDD:275368	4/15 (27%)
		C2H2 Zn finger	247..267	CDD:275368	2/19 (11%)
		C2H2 Zn finger	282..302	CDD:275368	1/19 (5%)
		zf-C2H2	306..328	CDD:278523	7/21 (33%)
		COG5048	307..>356	CDD:227381	18/48 (38%)
CG4820	NP_001097748.1	zf-AD	4..75	CDD:285071
		C2H2 Zn finger	224..244	CDD:275368	6/19 (32%)
		C2H2 Zn finger	252..272	CDD:275368	6/19 (32%)
		C2H2 Zn finger	279..297	CDD:275368	5/17 (29%)
		C2H2 Zn finger	322..339	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457232
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930