DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sna and snai2

DIOPT Version :9

Sequence 1:	NP_476732.1	Gene:	sna / 34908	FlyBaseID:	FBgn0003448	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_989424.1	Gene:	snai2 / 395065	XenbaseID:	XB-GENE-487371	Length:	266	Species:	Xenopus tropicalis

Alignment Length:	270	Identity:	123/270 - (45%)
Similarity:	148/270 - (54%)	Gaps:	43/270 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   118 PTTINPFQSAFVMAAGCNPISALWSSYQPHLAAFPSPASSMASPQSVYSYQQMTPPSSPGSDLET 182
            |.::.| |.....:...:||:.......|.|.:..||.|...|     |..:::||  |.||
Frog    38 PVSVLP-QPELYSSVAYSPITVWTGLLHPPLPSDLSPLSGYPS-----SLGRVSPP--PQSD--- 91

  Fly   183 GSEPEDLSVRNDIPLPALFHLFDEAKSSSSGASVSSSSGYSYTPAMSASSASVAANHAKNYRFKC 247
                                  ..:|..|...|..|.........:|.|.|..|.      :|:|
Frog    92 ----------------------TSSKDHSGSESPISDEEERLQTKLSDSHAIEAE------KFQC 128

  Fly   248 DECQKMYSTSMGLSKHRQFHCPAAECNQEKKTHSCEECGKLYTTIGALKMHIRTHTLPCKCPICG 312
            ..|.|.|||..||:||:|.||.|    |.:|:.||:.|.|.|.::||||||||||||||.|.|||
Frog   129 SLCSKTYSTFSGLAKHKQLHCDA----QSRKSFSCKYCEKEYVSLGALKMHIRTHTLPCVCKICG 189

  Fly   313 KAFSRPWLLQGHIRTHTGEKPFQCPDCPRSFADRSNLRAHQQTHVDVKKYACQVCHKSFSRMSLL 377
            ||||||||||||||||||||||.||.|.|:||||||||||.|||.|||||.|:.|.|:|||||||
Frog   190 KAFSRPWLLQGHIRTHTGEKPFSCPHCNRAFADRSNLRAHLQTHSDVKKYQCKNCSKTFSRMSLL 254

  Fly   378 NKHSSSNCTI 387
            :||..|.|.:
Frog   255 HKHEESGCCV 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sna	NP_476732.1	C2H2 Zn finger	308..328	CDD:275368	18/19 (95%)
		zf-H2C2_2	321..344	CDD:290200	18/22 (82%)
		zf-C2H2	334..356	CDD:278523	16/21 (76%)
		C2H2 Zn finger	336..356	CDD:275368	15/19 (79%)
		zf-H2C2_2	348..373	CDD:290200	17/24 (71%)
		C2H2 Zn finger	364..380	CDD:275368	10/15 (67%)
		C2H2 Zn finger	247..267	CDD:275368	11/19 (58%)
		C2H2 Zn finger	282..302	CDD:275368	12/19 (63%)
		zf-C2H2	306..328	CDD:278523	19/21 (90%)
		COG5048	307..>356	CDD:227381	41/48 (85%)
snai2	NP_989424.1	DUF4764	82..>160	CDD:292583	31/114 (27%)
		C2H2 Zn finger	128..148	CDD:275370	11/19 (58%)
		C2H2 Zn finger	159..179	CDD:275368	12/19 (63%)
		C2H2 Zn finger	185..205	CDD:275368	18/19 (95%)
		zf-H2C2_2	198..221	CDD:290200	18/22 (82%)
		zf-C2H2	211..233	CDD:278523	16/21 (76%)
		C2H2 Zn finger	213..233	CDD:275368	15/19 (79%)
		zf-H2C2_2	225..250	CDD:290200	17/24 (71%)
		C2H2 Zn finger	241..257	CDD:275368	10/15 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	50	1.000	Domainoid score	I11448
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004977
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR24388
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.010