DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sna and D19B

DIOPT Version :9

Sequence 1:	NP_476732.1	Gene:	sna / 34908	FlyBaseID:	FBgn0003448	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_477297.1	Gene:	D19B / 38717	FlyBaseID:	FBgn0022699	Length:	774	Species:	Drosophila melanogaster

Alignment Length:	179	Identity:	55/179 - (30%)
Similarity:	76/179 - (42%)	Gaps:	39/179 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   239 HAKNYR----FKC--DECQKMYSTSMGLSKHRQ--------FH-CPAAECNQE-----------K 277
            |.|::.    |:|  :.|:|.::|:.||..|.:        .| |....||:.           |
  Fly   271 HMKHHNDLLPFQCTVESCRKGFTTANGLRVHVEHAHTETSAMHPCTYEGCNKSFARPVLLSFHMK 335

  Fly   278 KTHS---------CEECGKLYTTIGALKMHIRTHT---LPCKCPICGKAFSRPWLLQGHIRTHTG 330
            :.|.         |.||.|::....|||.|:..||   ||..|.||||.|....:|:.|:..|.|
  Fly   336 RVHKVDTPQRDFPCTECEKVFRCPTALKKHMYKHTGEELPFACEICGKRFPINSVLRDHLLRHAG 400

  Fly   331 EKPFQCPDCPRSFADRSNLRAHQQTHVDVKKYACQVC-HKSFSRMSLLN 378
            .|...||.|......|.....|..||...|||.|:.| |.|.::.:|.|
  Fly   401 IKNHVCPYCGVGKTTRQEWNKHILTHTKEKKYECRQCDHASHNKQALAN 449

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sna	NP_476732.1	C2H2 Zn finger	308..328	CDD:275368	8/19 (42%)
		zf-H2C2_2	321..344	CDD:290200	8/22 (36%)
		zf-C2H2	334..356	CDD:278523	5/21 (24%)
		C2H2 Zn finger	336..356	CDD:275368	5/19 (26%)
		zf-H2C2_2	348..373	CDD:290200	10/25 (40%)
		C2H2 Zn finger	364..380	CDD:275368	6/16 (38%)
		C2H2 Zn finger	247..267	CDD:275368	7/29 (24%)
		C2H2 Zn finger	282..302	CDD:275368	8/19 (42%)
		zf-C2H2	306..328	CDD:278523	8/21 (38%)
		COG5048	307..>356	CDD:227381	16/48 (33%)
D19B	NP_477297.1	zf-AD	12..83	CDD:214871
		C2H2 Zn finger	255..275	CDD:275368	2/3 (67%)
		C2H2 Zn finger	283..335	CDD:275368	11/51 (22%)
		C2H2 Zn finger	318..338	CDD:275368	3/19 (16%)
		COG5048	<347..512	CDD:227381	39/103 (38%)
		C2H2 Zn finger	349..369	CDD:275368	8/19 (42%)
		C2H2 Zn finger	378..398	CDD:275368	8/19 (42%)
		C2H2 Zn finger	406..426	CDD:275368	5/19 (26%)
		C2H2 Zn finger	434..455	CDD:275368	6/16 (38%)
		C2H2 Zn finger	463..483	CDD:275368
		C2H2 Zn finger	491..511	CDD:275368
		C2H2 Zn finger	586..607	CDD:275368
		C2H2 Zn finger	615..635	CDD:275368
		zf-H2C2_2	627..652	CDD:290200
		C2H2 Zn finger	643..663	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24388
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100