DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sna and CG10274

DIOPT Version :9

Sequence 1:	NP_476732.1	Gene:	sna / 34908	FlyBaseID:	FBgn0003448	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_001097525.1	Gene:	CG10274 / 38716	FlyBaseID:	FBgn0035690	Length:	863	Species:	Drosophila melanogaster

Alignment Length:	300	Identity:	77/300 - (25%)
Similarity:	100/300 - (33%)	Gaps:	92/300 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   156 SSMASPQSVYSYQQMTPPSSPGSD-----------------------------LETGSEPED--- 188
            ||..|.:.:.......|.||.|.|                             ..||||.||
  Fly   184 SSEESEEDIDQDVDFEPNSSDGDDDVPLAQRLRDNSRMIPKAKAAVIKEEDQEFPTGSEEEDEDG 248

  Fly   189 ---LSVRNDIPLPALFHLFDEAKSSSSGASVSSSSGYSYTPAMSASSASVAANHAKNYR----FK 246
               .|.|..|| |...||...............:..|.              .|.|::.    |:
  Fly   249 EKSKSRRKRIP-PGERHLHRIIDCHICHQKFKKAIRYE--------------EHMKHHNDLLPFQ 298

  Fly   247 C--DECQKMYSTSMGLSKH-RQFHCPAAE---CNQE----------------KKTHS-------- 281
            |  :.|:|.::|:.||..| ...|...:|   ||.:                ||.|.
  Fly   299 CKVETCRKGFTTAGGLRLHIDHAHTELSEVHSCNVDGCGKTFPRIRLLTFHMKKMHGITKAAAPP 363

  Fly   282 ----CEECGKLYTTIGALKMHIRTH---TLPCKCPICGKAFSRPWLLQGHIRTHTGEKPFQCPDC 339
                |.||.|::....|||.|:..|   .||..|.||||.|.....|:.|:..|.|.|.:.||.|
  Fly   364 RDYPCTECEKVFRCPMALKKHMYKHDGKELPFPCNICGKRFVINSALKDHLMRHAGIKNYVCPYC 428

  Fly   340 PRSFADRSNLRAHQQTHVDVKKYACQVC-HKSFSRMSLLN 378
            ......|.....|..||...||:.|.:| |.|.::.||.|
  Fly   429 GVGKTTRQEWNTHILTHTQEKKFKCHICEHASHNKQSLAN 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sna	NP_476732.1	C2H2 Zn finger	308..328	CDD:275368	8/19 (42%)
		zf-H2C2_2	321..344	CDD:290200	8/22 (36%)
		zf-C2H2	334..356	CDD:278523	5/21 (24%)
		C2H2 Zn finger	336..356	CDD:275368	5/19 (26%)
		zf-H2C2_2	348..373	CDD:290200	9/25 (36%)
		C2H2 Zn finger	364..380	CDD:275368	6/15 (40%)
		C2H2 Zn finger	247..267	CDD:275368	7/22 (32%)
		C2H2 Zn finger	282..302	CDD:275368	8/19 (42%)
		zf-C2H2	306..328	CDD:278523	8/21 (38%)
		COG5048	307..>356	CDD:227381	16/48 (33%)
CG10274	NP_001097525.1	zf-AD	15..90	CDD:214871
		C2H2 Zn finger	334..353	CDD:275368	1/18 (6%)
		C2H2 Zn finger	368..388	CDD:275368	8/19 (42%)
		COG5048	394..729	CDD:227381	27/74 (36%)
		C2H2 Zn finger	397..417	CDD:275368	8/19 (42%)
		C2H2 Zn finger	425..445	CDD:275368	5/19 (26%)
		C2H2 Zn finger	453..474	CDD:275368	6/15 (40%)
		C2H2 Zn finger	482..502	CDD:275368
		C2H2 Zn finger	510..530	CDD:275368
		C2H2 Zn finger	638..659	CDD:275368
		C2H2 Zn finger	667..687	CDD:275368
		zf-H2C2_2	680..704	CDD:290200
		C2H2 Zn finger	695..715	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24388
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100