DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sna and scrt

DIOPT Version :9

Sequence 1:	NP_476732.1	Gene:	sna / 34908	FlyBaseID:	FBgn0003448	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_001261390.1	Gene:	scrt / 38469	FlyBaseID:	FBgn0004880	Length:	653	Species:	Drosophila melanogaster

Alignment Length:	415	Identity:	126/415 - (30%)
Similarity:	184/415 - (44%)	Gaps:	91/415 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 YKSCPLKKRPIVFVEERLPQTE-------ALALTKDSQF-AQDQPQDLSLKRGRDEETQDY---- 57
            |:...|..:|......|:|..|       .|.|:..:.| ...||..|..::.:.::...:
  Fly   246 YRPYSLDDKPAHGYRRRVPAEEDLHAAHAILDLSASTAFHPPTQPHQLQQQQQQQQQQHQHHHSQ 310

  Fly    58 -QQPEPKRDYVLNLSKTPERNSSSSSNSCLLSPPVEAQDYLPT-EIHMRGLTAGTTGYTTATPTT 120
             |...|::.:.|.|.:..::.:..:              :||| |.|....:..:.....|..:.
  Fly   311 QQHLAPQQHHYLPLQQQQQQQAHHT--------------HLPTLEAHAHLRSTSSIAELAAAASV 361

  Fly   121 INPFQSAFVMAAGCNPISALWSSYQPHLAAFPSPASSMASPQSVYSYQQMTPPSSPGSD--LETG 183
            :|..:          |.|...|:...|:.:.||..||.:|.| |.:....|..::|..|  |:.|
  Fly   362 VNEQR----------PASNASSASSNHMPSSPSSNSSSSSSQ-VQNENSNTTNTNPDGDGCLQDG 415

  Fly   184 SEPEDLSVRNDIPLPALFHLFDEAKSSSSGASVSSSSGYSYT------------------PAMSA 230
            ..                          ||||.:|:...:||                  ||.:|
  Fly   416 EH--------------------------SGASGASAKTVAYTYEAFFVSDGRSKRKHVADPAAAA 454

  Fly   231 SSASVAANHAKNYRFKCDECQKMYSTSMGLSKHRQFHCPAAECNQEKKTHSCEECGKLYTTIGAL 295
            |  .|.....:..::.|.||.|.|:||..||:|:|.| .:.:....||   |..|||.|.::.||
  Fly   455 S--GVPTPDQQKTKYTCSECGKQYATSSNLSRHKQTH-RSLDSQSAKK---CHTCGKAYVSMPAL 513

  Fly   296 KMHIRTHTLPCKCPICGKAFSRPWLLQGHIRTHTGEKPFQCPDCPRSFADRSNLRAHQQTHVDVK 360
            .||:.||.|...|.:|||.||||||||||:|:||||||:.|..|.::||||||||||.|||...|
  Fly   514 AMHLLTHKLSHSCGVCGKLFSRPWLLQGHLRSHTGEKPYGCAHCGKAFADRSNLRAHMQTHSVDK 578

  Fly   361 KYACQVCHKSFSRMSLLNKHSSSNC 385
            .:.|:.|||:|:..|.||||..|.|
  Fly   579 NFECKRCHKTFALKSYLNKHLESAC 603

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sna	NP_476732.1	C2H2 Zn finger	308..328	CDD:275368	15/19 (79%)
		zf-H2C2_2	321..344	CDD:290200	13/22 (59%)
		zf-C2H2	334..356	CDD:278523	13/21 (62%)
		C2H2 Zn finger	336..356	CDD:275368	13/19 (68%)
		zf-H2C2_2	348..373	CDD:290200	14/24 (58%)
		C2H2 Zn finger	364..380	CDD:275368	8/15 (53%)
		C2H2 Zn finger	247..267	CDD:275368	11/19 (58%)
		C2H2 Zn finger	282..302	CDD:275368	9/19 (47%)
		zf-C2H2	306..328	CDD:278523	15/21 (71%)
		COG5048	307..>356	CDD:227381	34/48 (71%)
scrt	NP_001261390.1	zf-C2H2	467..489	CDD:278523	11/21 (52%)
		C2H2 Zn finger	469..489	CDD:275370	11/19 (58%)
		C2H2 Zn finger	500..520	CDD:275368	9/19 (47%)
		COG5048	520..>617	CDD:227381	51/84 (61%)
		C2H2 Zn finger	526..546	CDD:275368	15/19 (79%)
		zf-H2C2_2	539..562	CDD:290200	13/22 (59%)
		C2H2 Zn finger	554..574	CDD:275368	13/19 (68%)
		zf-C2H2	554..574	CDD:278523	13/19 (68%)
		zf-H2C2_2	566..590	CDD:290200	13/23 (57%)
		C2H2 Zn finger	582..599	CDD:275368	9/16 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457098
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2462
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D37106at7147
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.750