DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sna and prg

DIOPT Version :9

Sequence 1:	NP_476732.1	Gene:	sna / 34908	FlyBaseID:	FBgn0003448	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_001260253.1	Gene:	prg / 34177	FlyBaseID:	FBgn0285971	Length:	558	Species:	Drosophila melanogaster

Alignment Length:	221	Identity:	64/221 - (28%)
Similarity:	90/221 - (40%)	Gaps:	37/221 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   179 DLETGSEPEDLSVRNDIPLPALFHLFDEAKSSSSGASVSSSSG----------------YSYTPA 227
            |.|.|...||:    |:||..      :|...::..||::::.                ..:|..
  Fly   166 DEEDGQNGEDV----DMPLGM------DAAQMAAQQSVANNANTTEARPKRAFLCQYCDLGFTLP 220

  Fly   228 MSASSASVAANHAKNYRFKCDECQKMYSTSMGLSKH-RQFHCPAAECNQEKKTHSCEECGKLYTT 291
            .......:|| |..|..:.|:.|.....|...|..| :..|.|       .:.:.|..|.|.:..
  Fly   221 AECQEHELAA-HDPNAPYCCNFCNIKLVTRPALISHIKTLHDP-------DRPYVCAHCRKGFVR 277

  Fly   292 IGALKMHIRTHT--LPCKCPICGKAFSRPWLLQGHIRTHTGEKPFQCPDCPRSFADRSNLRAHQQ 354
            ...||.|...||  .|..|.:|.|:|||...|..|:|.|:|.|||.|..|||||.....:..|.:
  Fly   278 RSDLKKHTIVHTGVRPFTCNVCSKSFSRNTNLTKHMRIHSGVKPFVCQQCPRSFQTAVEMMRHTR 342

  Fly   355 THVDVKKYACQVCHKSFSRMSLLNKH 380
            :|.:||.:.|..|..||||...|..|
  Fly   343 SHGEVKAFQCGRCPYSFSRRDKLIAH 368

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sna	NP_476732.1	C2H2 Zn finger	308..328	CDD:275368	9/19 (47%)
		zf-H2C2_2	321..344	CDD:290200	13/22 (59%)
		zf-C2H2	334..356	CDD:278523	8/21 (38%)
		C2H2 Zn finger	336..356	CDD:275368	7/19 (37%)
		zf-H2C2_2	348..373	CDD:290200	8/24 (33%)
		C2H2 Zn finger	364..380	CDD:275368	7/15 (47%)
		C2H2 Zn finger	247..267	CDD:275368	5/20 (25%)
		C2H2 Zn finger	282..302	CDD:275368	6/19 (32%)
		zf-C2H2	306..328	CDD:278523	9/21 (43%)
		COG5048	307..>356	CDD:227381	21/48 (44%)
prg	NP_001260253.1	zf-AD	16..94	CDD:285071
		COG5048	<212..340	CDD:227381	41/135 (30%)
		C2H2 Zn finger	239..260	CDD:275368	5/20 (25%)
		C2H2 Zn finger	268..288	CDD:275368	6/19 (32%)
		zf-H2C2_2	280..305	CDD:290200	10/24 (42%)
		zf-C2H2	294..316	CDD:278523	9/21 (43%)
		C2H2 Zn finger	296..316	CDD:275368	9/19 (47%)
		zf-H2C2_2	308..331	CDD:290200	12/22 (55%)
		C2H2 Zn finger	324..344	CDD:275368	7/19 (37%)
		C2H2 Zn finger	352..372	CDD:275368	8/17 (47%)
		C2H2 Zn finger	416..436	CDD:275368
		C2H2 Zn finger	443..464	CDD:275368
		C2H2 Zn finger	470..490	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24388
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100