DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sna and Cf2

DIOPT Version :9

Sequence 1:	NP_476732.1	Gene:	sna / 34908	FlyBaseID:	FBgn0003448	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_001350854.1	Gene:	Cf2 / 33692	FlyBaseID:	FBgn0000286	Length:	537	Species:	Drosophila melanogaster

Alignment Length:	343	Identity:	83/343 - (24%)
Similarity:	134/343 - (39%)	Gaps:	76/343 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 LPQTEALALTKDSQFAQDQPQDLSLK----------RGRDEETQDYQQPEPKRDYVLNLSKTPER 76
            :.|.|| |:|.|.|.....|:|:.|.          :......|.:||.:.::.....|.:..:|
  Fly   197 MEQQEA-AVTPDDQLPAMAPRDMRLTPEEQHHQQQLQAEHHHQQQHQQQQQQQQQQQELLEQQQR 260

  Fly    77 NSSSSSNSCLLSPPVEAQDYLPTEIHMRGLTAGTTGYTTATPTTINPFQSAFVMAAGCNPISALW 141
            .....:....:....:.||....::.::           ..|.|:.
  Fly   261 EMQEQAQQQQVHHHQQDQDLAGDQVALK-----------VPPLTVK------------------- 295

  Fly   142 SSYQPHLAAFPSPASSMASPQSVYSYQQMTPPSSPGSDLETGSEPEDLSVRNDIPLPALFHLFDE 206
                         .:..|:..::.|:.|:.....|.|..::|      .|.|.:|:.|:
  Fly   296 -------------LNKNANGGAIVSHPQVIIKEEPLSLSDSG------DVVNSVPVYAI------ 335

  Fly   207 AKSSSSGASVSSSSGYSYTPAMSASSASVAANHAKNYRFKCDECQKMYSTSMGLSKHRQFHCPAA 271
              .::.|....:|||      :...:.:|.|:.|...|.||.:|.|.:.|...|:.||:.|...|
  Fly   336 --QANPGVPAPASSG------VLVGTQTVPADLAHKIRHKCPDCPKTFKTPGTLAMHRKIHTGEA 392

  Fly   272 ECNQEKKTHSCEECGKLYTTIGALKMHIRTHT--LPCKCPICGKAFSRPWLLQGHIRTHTGEKPF 334
            :...:::.::|..|||.:|....||.|.|.||  .|..|..|.|:||....|..||||||||||:
  Fly   393 DATPKERPYTCSYCGKSFTQSNTLKQHTRIHTGEKPFHCGYCEKSFSVKDYLTKHIRTHTGEKPY 457

  Fly   335 QCPDCPRSFADRSNLRAH 352
            .||.|.:.|..||.|..|
  Fly   458 TCPYCDKRFTQRSALTVH 475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sna	NP_476732.1	C2H2 Zn finger	308..328	CDD:275368	9/19 (47%)
		zf-H2C2_2	321..344	CDD:290200	14/22 (64%)
		zf-C2H2	334..356	CDD:278523	8/19 (42%)
		C2H2 Zn finger	336..356	CDD:275368	8/17 (47%)
		zf-H2C2_2	348..373	CDD:290200	2/5 (40%)
		C2H2 Zn finger	364..380	CDD:275368
		C2H2 Zn finger	247..267	CDD:275368	7/19 (37%)
		C2H2 Zn finger	282..302	CDD:275368	9/19 (47%)
		zf-C2H2	306..328	CDD:278523	9/21 (43%)
		COG5048	307..>356	CDD:227381	24/46 (52%)
Cf2	NP_001350854.1	COG5048	<366..>473	CDD:227381	44/106 (42%)
		C2H2 Zn finger	368..388	CDD:275368	7/19 (37%)
		C2H2 Zn finger	403..423	CDD:275368	9/19 (47%)
		C2H2 Zn finger	431..451	CDD:275368	9/19 (47%)
		zf-H2C2_2	443..468	CDD:316026	15/24 (63%)
		C2H2 Zn finger	459..480	CDD:275368	8/17 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468417
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	54	1.000	Inparanoid score	I1809
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24388
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.990