DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sna and CG1529

DIOPT Version :9

Sequence 1:	NP_476732.1	Gene:	sna / 34908	FlyBaseID:	FBgn0003448	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_001138223.2	Gene:	CG1529 / 33077	FlyBaseID:	FBgn0031144	Length:	512	Species:	Drosophila melanogaster

Alignment Length:	273	Identity:	64/273 - (23%)
Similarity:	98/273 - (35%)	Gaps:	83/273 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   177 GSDLETGSEPED----LSVRNDIPLPALFHLFDEAKSS----SSGASVSSSSGYS---------Y 224
            |..::...:.||    |..|.|...|      ||.::|    |.|......:|.:         .
  Fly   122 GQQVDLSKKQEDQKKILDDREDEEYP------DEYENSQQQLSQGTGSKRRAGLACDQCGKQVYK 180

  Fly   225 TPAMSASSASVAANHAKNY----------RFK------------------------CDECQKMYS 255
            .|.:.|...||...::|.:          |::                        |:.|.:.||
  Fly   181 LPYLEAHIRSVHQGYSKPFLCRSCDKSFTRYEQLRSHMRNAHPQLEQLQQELRDLICELCNRQYS 245

  Fly   256 TSMGLSKHRQFHCPAAECNQEKKTHSCEECGKLYTTIGALKMHIRTHTLPC----KCPICGKAFS 316
            |...|.:|.:.|.       ::|.|.||.||....|...|..|:|||. |.    ||..|.:.|.
  Fly   246 TKNALGEHLKRHA-------QRKEHVCEHCGVAKVTRTELLTHLRTHN-PTWERFKCEQCPQLFR 302

  Fly   317 RPWLLQGHIR-THTGEKPFQCPDCPRSFADRSNLRAHQQTHVDVK---------KYACQVCHK-S 370
            ....:..|:| .|.|::.|||..|.:.|...::...|::.|.:..         .:||..|.| .
  Fly   303 HKSAISRHVRVVHEGQRRFQCGHCEKKFGTHASQVRHERLHTESTGSGEAAEEWPFACIHCQKPC 367

  Fly   371 FSRMSL---LNKH 380
            .||.:|   |.:|
  Fly   368 VSRQTLELHLRRH 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sna	NP_476732.1	C2H2 Zn finger	308..328	CDD:275368	5/20 (25%)
		zf-H2C2_2	321..344	CDD:290200	8/23 (35%)
		zf-C2H2	334..356	CDD:278523	6/21 (29%)
		C2H2 Zn finger	336..356	CDD:275368	4/19 (21%)
		zf-H2C2_2	348..373	CDD:290200	6/34 (18%)
		C2H2 Zn finger	364..380	CDD:275368	7/19 (37%)
		C2H2 Zn finger	247..267	CDD:275368	7/19 (37%)
		C2H2 Zn finger	282..302	CDD:275368	8/19 (42%)
		zf-C2H2	306..328	CDD:278523	6/26 (23%)
		COG5048	307..>356	CDD:227381	14/49 (29%)
CG1529	NP_001138223.2	zf-AD	11..79	CDD:285071
		C2H2 Zn finger	171..192	CDD:275368	3/20 (15%)
		zf-C2H2_2	201..>257	CDD:289522	8/55 (15%)
		C2H2 Zn finger	201..222	CDD:275368	1/20 (5%)
		C2H2 Zn finger	237..257	CDD:275368	7/19 (37%)
		C2H2 Zn finger	265..285	CDD:275368	8/19 (42%)
		zf-C2H2_8	268..349	CDD:292531	24/81 (30%)
		C2H2 Zn finger	294..315	CDD:275368	5/20 (25%)
		C2H2 Zn finger	323..343	CDD:275368	4/19 (21%)
		C2H2 Zn finger	360..380	CDD:275368	7/19 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457190
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930