DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sna and snai1a

DIOPT Version :9

Sequence 1:	NP_476732.1	Gene:	sna / 34908	FlyBaseID:	FBgn0003448	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_001300628.1	Gene:	snai1a / 30273	ZFINID:	ZDB-GENE-990415-255	Length:	260	Species:	Danio rerio

Alignment Length:	318	Identity:	117/318 - (36%)
Similarity:	144/318 - (45%)	Gaps:	83/318 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 NLSKTPERNSSSSSNSCLLSPPVEAQDYLPTEIHMRGLTAGTTGYTTATPTTINPFQSAFVMAAG 133
            |.|:...:|.:|.....|...|..:.|:                     |.|
Zfish    17 NYSELECQNDTSPDRYPLAELPAVSNDF---------------------PVT------------- 47

  Fly   134 CNPISALWS-SYQPHLAAFPSPASSMASPQSVYSYQQMTPPSSPGSDLETGSEPEDLSVRNDIPL 197
            |.....:|. |..|.|...||| |::::.|.....      |||.|...:.|..||....:|.|.
Zfish    48 CLTTGLVWDVSLLPSLHNSPSP-STLSTNQGPLDL------SSPSSISCSSSGEEDEGRTSDPPS 105

  Fly   198 PALFHLFDEAKSSSSGASVSSSSGYSYTPAMSASSASVAANHAKNYRFKCDECQKMYSTSMGLSK 262
            |.....:...::|....|..|.:|    .....|.|:|.|  |....|.|.
Zfish   106 PDSSDTYHPQQTSRPRRSNKSRAG----QREDKSEAAVTA--ASRPAFFCK-------------- 150

  Fly   263 HRQFHCPAAECNQEKKTHSCEECGKLYTTIGALKMHIRTHTLPCKCPICGKAFSRPWLLQGHIRT 327
                |||                 |.|.::||||||||:|||||.||.|||||||||||:|||||
Zfish   151 ----HCP-----------------KEYNSLGALKMHIRSHTLPCVCPTCGKAFSRPWLLRGHIRT 194

  Fly   328 HTGEKPFQCPDCPRSFADRSNLRAHQQTHVDVKKYACQVCHKSFSRMSLLNKHSSSNC 385
            ||||:||.||.|.|:||||||||||.|||.|||||.|..|.::|||||||.|||::.|
Zfish   195 HTGERPFSCPHCNRAFADRSNLRAHLQTHADVKKYQCSTCSRTFSRMSLLQKHSAAGC 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sna	NP_476732.1	C2H2 Zn finger	308..328	CDD:275368	17/19 (89%)
		zf-H2C2_2	321..344	CDD:290200	16/22 (73%)
		zf-C2H2	334..356	CDD:278523	16/21 (76%)
		C2H2 Zn finger	336..356	CDD:275368	15/19 (79%)
		zf-H2C2_2	348..373	CDD:290200	16/24 (67%)
		C2H2 Zn finger	364..380	CDD:275368	9/15 (60%)
		C2H2 Zn finger	247..267	CDD:275368	1/19 (5%)
		C2H2 Zn finger	282..302	CDD:275368	10/19 (53%)
		zf-C2H2	306..328	CDD:278523	18/21 (86%)
		COG5048	307..>356	CDD:227381	39/48 (81%)
snai1a	NP_001300628.1	C2H2 Zn finger	149..169	CDD:275368	14/54 (26%)
		COG5048	<170..>244	CDD:227381	57/73 (78%)
		zf-C2H2	173..195	CDD:278523	18/21 (86%)
		C2H2 Zn finger	175..195	CDD:275368	17/19 (89%)
		zf-H2C2_2	188..211	CDD:290200	16/22 (73%)
		zf-C2H2	201..223	CDD:278523	16/21 (76%)
		C2H2 Zn finger	203..223	CDD:275368	15/19 (79%)
		C2H2 Zn finger	231..247	CDD:275368	9/15 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	50	1.000	Domainoid score	I11673
eggNOG	1	0.900	-	-		E1_KOG2462
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	221	1.000	Inparanoid score	I3523
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24388
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	7	6.920