Protein Alignment sna and Snai2

DIOPT Version :10

• Sequence 1: NP_476732.1
• Gene: sna / 34908
• FlyBaseID: FBgn0003448
• Length: 390
• Species: Drosophila melanogaster
• Sequence 2: NP_035545.1
• Gene: Snai2 / 20583
• MGIID: 1096393
• Length: 269
• Species: Mus musculus
• Alignment Length: 321
• Identity: 134/321 - (41%)
• Similarity: 166/321 - (51%)
• Gaps: 67/321 - (20%)

  Fly    69 NLSKTPERNSSSSSNSCLLSPPVEAQDYLPTEIHMRGLTAGTTGYTTATPTTINPFQSAFVMAAG 133
            |.||.| ..|...:::.::||.:.....:|.......||:|     ..:|.|:
Mouse    12 NASKKP-NYSELDTHTVIISPYLYESYPIPVIPKPEILTSG-----AYSPITV------------ 58

  Fly   134 CNPISALWSSYQPHLAAFPSPASSMASPQSVYSYQ--QMTPPSSPGSDLETGSEPEDLSVRNDIP 196
                   |:|   ..|...||..|..||.:.||..  :::||  |.||
Mouse    59 -------WTS---SAAPLHSPLPSGLSPLTGYSSSLGRVSPP--PSSD----------------- 94

  Fly   197 LPALFHLFDEAKSSSSGASVSSSSGYSYTPAMSASSASVAANHAKNYRFKCDECQKMYSTSMGLS 261
                    ..:|..|...|..|.......|.:|...|..|.      :|:|:.|.|.|||..||:
Mouse    95 --------TSSKDHSGSESPISDEEERLQPKLSDPHAIEAE------KFQCNLCNKTYSTFSGLA 145

  Fly   262 KHRQFHCPAAECNQEKKTHSCEECGKLYTTIGALKMHIRTHTLPCKCPICGKAFSRPWLLQGHIR 326
            ||:|.||.|    |.:|:.||:.|.|.|.::||||||||||||||.|.|||||||||||||||||
Mouse   146 KHKQLHCDA----QSRKSFSCKYCDKEYVSLGALKMHIRTHTLPCVCKICGKAFSRPWLLQGHIR 206

  Fly   327 THTGEKPFQCPDCPRSFADRSNLRAHQQTHVDVKKYACQVCHKSFSRMSLLNKHSSSNCTI 387
            ||||||||.||.|.|:||||||||||.|||.|||||.|:.|.|:|||||||:||..|.|.:
Mouse   207 THTGEKPFSCPHCNRAFADRSNLRAHLQTHSDVKKYQCKNCSKTFSRMSLLHKHEESGCCV 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sna	NP_476732.1	SFP1	<245..303	CDD:227516	31/57 (54%)
		C2H2 Zn finger	247..267	CDD:275368	11/19 (58%)
		C2H2 Zn finger	282..302	CDD:275368	12/19 (63%)
		zf-C2H2	306..328	CDD:395048	19/21 (90%)
		C2H2 Zn finger	308..328	CDD:275368	18/19 (95%)
		zf-H2C2_2	321..344	CDD:463886	18/22 (82%)
		zf-C2H2	334..356	CDD:395048	16/21 (76%)
		C2H2 Zn finger	336..356	CDD:275368	15/19 (79%)
		zf-H2C2_2	348..373	CDD:463886	17/24 (71%)
		C2H2 Zn finger	364..380	CDD:275368	10/15 (67%)
Snai2	NP_035545.1	SNAG domain. /evidence=ECO:0000250|UniProtKB:O43623	1..20		4/8 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	81..117		10/62 (16%)
		SFP1	<102..183	CDD:227516	37/90 (41%)
		C2H2 Zn finger	131..151	CDD:275370	11/19 (58%)
		C2H2 Zn finger	162..182	CDD:275368	12/19 (63%)
		C2H2 Zn finger	188..208	CDD:275368	18/19 (95%)
		zf-H2C2_2	201..224	CDD:463886	18/22 (82%)
		zf-C2H2	214..236	CDD:395048	16/21 (76%)
		C2H2 Zn finger	216..236	CDD:275368	15/19 (79%)
		zf-H2C2_2	228..253	CDD:463886	17/24 (71%)
		C2H2 Zn finger	244..260	CDD:275368	10/15 (67%)