DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment sna and Egr3

DIOPT Version :9

Sequence 1:NP_476732.1 Gene:sna / 34908 FlyBaseID:FBgn0003448 Length:390 Species:Drosophila melanogaster
Sequence 2:NP_061251.1 Gene:Egr3 / 13655 MGIID:1306780 Length:387 Species:Mus musculus


Alignment Length:409 Identity:87/409 - (21%)
Similarity:139/409 - (33%) Gaps:122/409 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly    20 ERLPQTEALALTK--DSQFAQDQPQDLSLKRGRDEETQDYQQ---------------PEPKRDYV 67
            |:||.|.:..|.:  |:.:.::.|..|:|..|..:....|.|               |.|:..|.
Mouse     7 EKLPVTMSSLLNQLPDNLYPEEIPSALNLFSGSSDSVAHYNQMATENVMDIGLTNEKPNPELSYS 71

  Fly    68 LNLSKTPERNS---------SSSSNSC------LLS------PPVEAQDYLPTEIHMRGLTAGTT 111
            .:....|...:         .|.||.|      |:|      ||                .:|..
Mouse    72 SSFQPAPGNKTVTYLGKFAFDSPSNWCQDNIISLMSAGILGVPP----------------ASGAL 120

  Fly   112 GYTTATPTTINPFQSAFVMAAGCNPISALWSSYQPHL---------AAFPSPASSMASPQSVYSY 167
            ...|:|.:.:.|.|         ..:.|::.:..|:.         .:|..|..:.....|...|
Mouse   121 STQTSTASMVQPPQ---------GDVEAMYPALPPYSNCGDLYSEPVSFHDPQGNPGLAYSPQDY 176

  Fly   168 QQMTP-------PSSPGSDL-----ETGSEPEDLSVRNDIPL----PALFHLFDEAKSSSSGASV 216
            |...|       |..|..:|     :.||.||....:...|:    |.:..|  |...:.....:
Mouse   177 QSAKPALDSNLFPMIPDYNLYHHPNDMGSIPEHKPFQGMDPIRVNPPPITPL--ETIKAFKDKQI 239

  Fly   217 SSSSGYSYTPAMSASSASVAANHAKNYRFKCDECQKMYSTSMGLSKHRQFHCPAAECNQEKKTHS 281
            ....|....|.::....                            :.|::....::....::.|:
Mouse   240 HPGFGSLPQPPLTLKPI----------------------------RPRKYPNRPSKTPLHERPHA 276

  Fly   282 C--EECGKLYTTIGALKMHIRTHT--LPCKCPICGKAFSRPWLLQGHIRTHTGEKPFQCPDCPRS 342
            |  |.|.:.::....|..|:|.||  .|.:|.||.::|||...|..|||||||||||.|..|.|.
Mouse   277 CPAEGCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRK 341

  Fly   343 FADRSNLRAHQQTHVDVKK 361
            ||.....:.|.:.|:..|:
Mouse   342 FARSDERKRHAKIHLKQKE 360

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
snaNP_476732.1 C2H2 Zn finger 308..328 CDD:275368 10/19 (53%)
zf-H2C2_2 321..344 CDD:290200 15/22 (68%)
zf-C2H2 334..356 CDD:278523 7/21 (33%)
C2H2 Zn finger 336..356 CDD:275368 6/19 (32%)
zf-H2C2_2 348..373 CDD:290200 3/14 (21%)
C2H2 Zn finger 364..380 CDD:275368
C2H2 Zn finger 247..267 CDD:275368 1/19 (5%)
C2H2 Zn finger 282..302 CDD:275368 6/21 (29%)
zf-C2H2 306..328 CDD:278523 10/21 (48%)
COG5048 307..>356 CDD:227381 24/48 (50%)
Egr3NP_061251.1 DUF3446 87..147 CDD:314753 14/84 (17%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 241..283 6/69 (9%)
COG5048 269..>333 CDD:227381 26/63 (41%)
C2H2 Zn finger 277..299 CDD:275368 6/21 (29%)
COG5048 303..>375 CDD:227381 27/58 (47%)
C2H2 Zn finger 307..327 CDD:275368 10/19 (53%)
C2H2 Zn finger 335..355 CDD:275368 6/19 (32%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 348..387 3/13 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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