Protein Alignment CG4161 and YMR027W

DIOPT Version :9

• Sequence 1: NP_001285955.1
• Gene: CG4161 / 34907
• FlyBaseID: FBgn0028892
• Length: 484
• Species: Drosophila melanogaster
• Sequence 2: NP_013740.1
• Gene: YMR027W / 855042
• SGDID: S000004629
• Length: 470
• Species: Saccharomyces cerevisiae
• Alignment Length: 490
• Identity: 134/490 - (27%)
• Similarity: 205/490 - (41%)
• Gaps: 90/490 - (18%)

  Fly    28 LSGRY----KQSFAYLTLRTRMPGIMQQIIMRLLSDLPDLVNKYGEEVRKDVKQIVDAVERLKME 88
            :.||:    |.:|...|..||.|.|:|..|        |.::|: :|..|......:..|.:|.|
Yeast     3 IPGRFMTIDKGTFGEYTASTRWPIIIQNAI--------DDLSKH-QETEKSNGTKFEQGEVIKKE 58

  Fly    89 LNRDRQFLLFHGAEPDKVEWNAF------ITEMP---------RPKKSFFRACWLHAECYLYRRI 138
            |...||.::      |:|....|      |..:|         .|:.::....||.:|.|||||:
Yeast    59 LKEFRQEII------DRVPLRPFTEEEIKIANVPLSFNEYLKKHPEVNWGAVEWLFSEVYLYRRV 117

  Fly   139 FSFFENSRHLQKYDCFDHLKKEDLMLS-----------EMAMSALARATRGLAKSYD-----AFS 187
            ...|:......|:|.|:.||:.....|           |..:..|....:......|     .|.
Yeast   118 NVLFQRQCEWAKFDIFNRLKQSTFESSFYGVVELALRYENLLPQLREMKQNPGNEIDDILKVLFK 182

  Fly   188 KLLRINLWGNHFEMQIGAFRFTEEDSKDDINVLVKVADIDRILLVDDTTLIWNCLVLASKSSGNR 252
            :.:.|:||||..::.: ....|.||.|.......:.|...:| :|:||...|..|..|...:.:|
Yeast   183 EFIEISLWGNATDLSL-LTNATLEDIKSIQGAKARAASESKI-VVNDTEKAWEVLTKARADANSR 245

  Fly   253 --IVDFICDNGGFEFFTDMLLLEYMVDNNLATQVRLHVKAIPWYISDVTRADIEWTLD------- 308
              .|||:.||.|||.:.|::|..:::.:.|||:...|.|.||:.:|||...|.:..:.
Yeast   246 EIRVDFVLDNSGFELYADLMLAAFLLQSGLATKCIFHAKDIPYMVSDVMLKDFDILVHDLRDREF 310

  Fly   309 FLTGH----RDECLSALGKKWTHMMNTQKIVIAPTSYFWTGPQPYFVMVESDIE-----LYRLLT 364
            |.:|.    ....|.....:....:::.||.....| |||....|:.:..::.:     |::.|.
Yeast   311 FPSGEPSTKESRALDLFAGEMEKFVSSGKIEFREDS-FWTTELDYWNLDANETKYHGSILHKDLQ 374

  Fly   365 TSKLAIFKGDLNYRKLLGDFIWDSTEEFITCLRGFRPTNI--CALRTVKCEVVCGLSEGLADSLL 427
            .|.|.|||||||||||.||..|..|.::.|.:.......|  .:|||.|.:|...|.||| |:.|
Yeast   375 KSNLVIFKGDLNYRKLTGDRKWPRTTKWETAIGPLATNGITSLSLRTCKADVQVALPEGL-DAKL 438

  Fly   428 KNDHN---------WMISGNYGVIQYTDSLKCSCA 453
            ..:..         |..||.:.||       |.|:
Yeast   439 SQEWEKENPGRGSWWCCSGKWAVI-------CFCS 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4161	NP_001285955.1	DUF89	40..426	CDD:280170	122/436 (28%)
YMR027W	NP_013740.1	DUF89	19..438	CDD:376673	122/437 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157341354
Domainoid	1	1.000	166	1.000	Domainoid score	I807
eggNOG	1	0.900	-	-		E1_KOG3870
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	178	1.000	Inparanoid score	I970
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58548
OrthoFinder	1	1.000	-	-		FOG0002784
OrthoInspector	1	1.000	-	-		otm46766
orthoMCL	1	0.900	-	-		OOG6_102304
Panther	1	1.100	-	-	O	PTHR12260
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1747
SonicParanoid	1	1.000	-	-		X1873
TreeFam	1	0.960	-	-
	14	13.790