DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4161 and SPAC806.04c

DIOPT Version :9

Sequence 1:	NP_001285955.1	Gene:	CG4161 / 34907	FlyBaseID:	FBgn0028892	Length:	484	Species:	Drosophila melanogaster
Sequence 2:	NP_592854.2	Gene:	SPAC806.04c / 2543077	PomBaseID:	SPAC806.04c	Length:	438	Species:	Schizosaccharomyces pombe

Alignment Length:	471	Identity:	137/471 - (29%)
Similarity:	207/471 - (43%)	Gaps:	83/471 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 FEGPTPRHSLLSGRYKQSFAYLTLRTRMPGIMQQIIMRLLSDLPDLVNKYG-----EEVRKDVKQ 77
            |..|...:|:.|.  .:||.:... ||..||   |:..:..|:.:.::|..     .||....|.
pombe     3 FLNPPFPYSMTSD--PESFGHECF-TRRWGI---ILTGIEKDVSERLSKLASTSKDSEVVAQGKP 61

  Fly    78 IVDAVERLKMELNRDRQFLLFHGAEPDKVEWNAFITEMPRPKKSFFRACWLHAECYLYRRIFSFF 142
            :::.:|..|.::..||..:...|...|.||:|..:.::  ...|:..|.||::|||.||||...|
pombe    62 LLNDLEAFKSDIKNDRPLVPLEGEGQDIVEYNEELKQL--DNASWGNAPWLYSECYYYRRISLIF 124

  Fly   143 ENSRHLQKYDCFDHLKKEDLMLSEMAMSALA-------RATRGLAK------SYDAFSKLLRINL 194
            ......:.||.|...|...|..|..|:..||       .....:||      :|..|.::.:|:|
pombe   125 ARYSEWKAYDPFFQQKDSTLKSSRAAVEELAGRYCLLEEELNSIAKKGDSHIAYMVFVEMAQISL 189

  Fly   195 WGN-----------HFEMQ-IGAFRFTEEDSKDDINVLVKVADIDRILLVDDTTLIWNCLVLASK 247
            |||           :.|:| :...:..||..|:              :||:|...:|:.|    |
pombe   190 WGNATDLSLLTNLSYEELQNLQGQKVVEESQKN--------------ILVNDFPTVWSKL----K 236

  Fly   248 SSGNRIVDFICDNGGFEFFTDMLLLEYMVDNNLATQVRLHVKAIPWYISDVTRADIEWTL----- 307
            ...|..:||:.||.|||.:.|::...|::...:|.::.||.|..||::|||...|||:.|
pombe   237 DVHNGRIDFVLDNAGFELYVDLIFAAYLLKAGIAKEIVLHPKDFPWFVSDVLPYDIEYLLTNLDT 301

  Fly   308 --------DFLTGHRDECLSALGKKWTHMMNTQKIVIAPTSYFWTGPQPYFVMVESDIELYRLLT 364
                    .|.|..|.  .||.|:           :...|..|||....:..|.:....|...|.
pombe   302 IFPTESVTKFATDLRS--FSAKGQ-----------LRLRTDPFWTTAHYFGRMPDFAAGLLTELE 353

  Fly   365 TSKLAIFKGDLNYRKLLGDFIWDSTEEFITCLRGF-RPTNICALRTVKCEVVCGLSEGLADSLLK 428
            .|.:..||||||||||.||.:|..|..|...|... ...|.|||||.|.:||.||.:||.:.:.|
pombe   354 KSDMIFFKGDLNYRKLTGDCLWPRTTPFGKTLGPIANAINACALRTCKADVVVGLPDGLYEKIAK 418

  Fly   429 NDHNWMISGNYGVIQY 444
            :..:|..:|.|.|:::
pombe   419 DLPHWERTGKYAVVEF 434

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4161	NP_001285955.1	DUF89	40..426	CDD:280170	126/429 (29%)
SPAC806.04c	NP_592854.2	DUF89	23..416	CDD:376673	126/429 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	189	1.000	Domainoid score	I735
eggNOG	1	0.900	-	-		E1_KOG3870
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	203	1.000	Inparanoid score	I984
OMA	1	1.010	-	-		QHG58548
OrthoFinder	1	1.000	-	-		FOG0002784
OrthoInspector	1	1.000	-	-		mtm9300
orthoMCL	1	0.900	-	-		OOG6_102304
Panther	1	1.100	-	-	O	PTHR12260
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1747
SonicParanoid	1	1.000	-	-		X1873
TreeFam	1	0.960	-	-
	13	12.860