DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4161 and SPCC1393.13

DIOPT Version :9

Sequence 1:	NP_001285955.1	Gene:	CG4161 / 34907	FlyBaseID:	FBgn0028892	Length:	484	Species:	Drosophila melanogaster
Sequence 2:	NP_587971.1	Gene:	SPCC1393.13 / 2538830	PomBaseID:	SPCC1393.13	Length:	442	Species:	Schizosaccharomyces pombe

Alignment Length:	461	Identity:	129/461 - (27%)
Similarity:	207/461 - (44%)	Gaps:	60/461 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 LFEGPTPRHSLLSGRYKQSFAYLTLRTRMPGIMQQIIMRLLSDLPDLVNKYGEEVRKDV------ 75
            |...|.| :::.|.  .:|:|.:.:..:.|.|...:|               :||.:::
pombe     5 LLHPPKP-YAMTSD--PESYASVCVMKKWPIIATNVI---------------DEVSRNISKALEA 51

  Fly    76 ------------KQIVDAVERLKMELNRDRQFLLFHGAEPDKVEWNAFITEMPRPKKSFFRACWL 128
                        |:|:..:.:||.:|..:|......|..||..::|..:.::  ...::..|.||
pombe    52 GMSDKAAYVTQGKEIISLLNQLKYDLQHNRPLKPLVGQGPDIDDYNEELEQV--GPLTWGDAPWL 114

  Fly   129 HAECYLYRRIFSFFENSRHLQKYDCFDHLKKEDLMLSEMAMSALAR----ATRGLAK-------- 181
            :|.||.||.:..||:......::|.|...|...|..|:.|:...|:    ....||.
pombe   115 YAGCYFYRIMSLFFQARSEWNRHDPFFEQKDFTLRSSKSAIEEFAKRYVHLNSELASIQENKDDK 179

  Fly   182 -SYDAFSKLLRINLWGNHFEMQIGAFRFTEEDSKDDINVLVKVADIDRILLVDDTTLIWNCLVLA 245
             :|..|.::..|:||||  .:.:|.......:....:.....|.:..:.:||:|...||:.|
pombe   180 AAYMIFVEMAEISLWGN--AIDLGLLVNATYEQLQSLQGQKAVEESQKNILVNDFPKIWSKL--- 239

  Fly   246 SKSSGNRIVDFICDNGGFEFFTDMLLLEYMVDNNLATQVRLHVKAIPWYISDVTRADIEWTLDFL 310
            ||....|| ||:.||.|||.|.|:|...|::...:|..:.||.|.:||::|||...||....:.|
pombe   240 SKVRHGRI-DFVLDNAGFELFVDLLFATYLLKTEIAETIILHPKDVPWFVSDVLVNDIPHLFNSL 303

  Fly   311 TGH-RDECLSALGKKWTHMMNTQKIVIAPTSYFWTGPQPYFVMVESDIELYRLLTTSKLAIFKGD 374
            |.: ..|.:..|...........||||.|.. |||....:..:.:...:|...|..|.:.|||||
pombe   304 TSYFSGEGVQKLASDLAEFHAEGKIVIRPNP-FWTTAHYFGRLPDVAPKLLSDLEQSDMVIFKGD 367

  Fly   375 LNYRKLLGDFIWDSTEEFITCLRGFR-PTNICALRTVKCEVVCGLSEGLADSLLKNDHNWMISGN 438
            ||:|||.||..|..|..|...|.... ..||.||||:|.:||.||.:|:.:.:.|::.:|..:|.
pombe   368 LNFRKLTGDCEWPHTTPFAEALGPIAGKFNILALRTIKADVVVGLGKGVYEEIAKDNPHWERTGK 432

  Fly   439 YGVIQY 444
            |.|:::
pombe   433 YAVVEF 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4161	NP_001285955.1	DUF89	40..426	CDD:280170	118/418 (28%)
SPCC1393.13	NP_587971.1	DUF89	25..420	CDD:376673	118/418 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	189	1.000	Domainoid score	I735
eggNOG	1	0.900	-	-		E1_KOG3870
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	203	1.000	Inparanoid score	I984
OMA	1	1.010	-	-		QHG58548
OrthoFinder	1	1.000	-	-		FOG0002784
OrthoInspector	1	1.000	-	-		mtm9300
orthoMCL	1	0.900	-	-		OOG6_102304
Panther	1	1.100	-	-	O	PTHR12260
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1747
SonicParanoid	1	1.000	-	-		X1873
TreeFam	1	0.960	-	-
	13	12.860