DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wor and snai3

DIOPT Version :9

Sequence 1:	NP_476601.1	Gene:	wor / 34906	FlyBaseID:	FBgn0001983	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	NP_001070853.1	Gene:	snai3 / 567724	ZFINID:	ZDB-GENE-061013-757	Length:	283	Species:	Danio rerio

Alignment Length:	342	Identity:	122/342 - (35%)
Similarity:	162/342 - (47%)	Gaps:	115/342 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   163 NNNLLKSIAEYEDCMKMQNIKEEIPPIP------------SPQLFYPPPTPLAEPEDLSVTQRRV 215
            :|:.||::..:::..          |:|            |..::.||..|....:|
Zfish    34 SNSKLKTLHPHQNMF----------PVPCYGNSAGWMNPISSDIYMPPQHPSLPIDD-------- 80

  Fly   216 LSENMNLQNVARALLSMQHMAPQHAPPPIDME---EDQENQDINQLKIKSSNDLYYQCQQCNKCY 277
                        .:|.:.:..|..:.|..||.   ...|:.|.:.|:: |..||:      .|..
Zfish    81 ------------PILGLTYPLPAPSSPLRDMRPALSMLEHTDPSSLQL-SHRDLH------EKVP 126

  Fly   278 ATYAGLVK--HQQTHAYESTEYKIIRSQPGGSGAIVDQTEFCTDQASALIQAANVASAQSMQKPV 340
            .:..||..  :.|.|:.|
Zfish   127 VSPLGLTTTGNSQEHSDE----------------------------------------------- 144

  Fly   341 GVPRYHCQDCGKSYSTYSGLSKHQQFHC--PSAEGNQVKKVFSCKNCDKTYVSLGALKMHIRTHT 403
                  |.||.|:|.::|.|:..:|.||  |      ..|.|:||.|:|.|||||||||||||||
Zfish   145 ------CFDCQKAYLSFSNLANQRQVHCQWP------CHKYFTCKYCEKEYVSLGALKMHIRTHT 197

  Fly   404 LPCKCPICGKAFSRPWLLQGHIRTHTGEKPFSCQHCNRAFADRSNLRAHMQTHSDVKKYSCPTCT 468
            |||.|.:||||||||||||||||||||||||:|.||:||||||||||||:||||::|||.|..|.
Zfish   198 LPCVCKLCGKAFSRPWLLQGHIRTHTGEKPFTCPHCSRAFADRSNLRAHLQTHSEIKKYQCRNCF 262

  Fly   469 KSFSRMSLLAKHLQSGC 485
            |:|||:|||.||.::||
Zfish   263 KTFSRISLLTKHEEAGC 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wor	NP_476601.1	C2H2 Zn finger	270..290	CDD:275368	4/21 (19%)
		C2H2 Zn finger	317..334	CDD:275368	0/16 (0%)
		zf-C2H2	345..367	CDD:278523	8/21 (38%)
		C2H2 Zn finger	347..367	CDD:275368	8/19 (42%)
		PHA00732	379..>417	CDD:177300	29/37 (78%)
		C2H2 Zn finger	382..402	CDD:275368	16/19 (84%)
		zf-C2H2_8	405..482	CDD:292531	60/76 (79%)
		zf-C2H2	406..428	CDD:278523	18/21 (86%)
		C2H2 Zn finger	408..428	CDD:275368	17/19 (89%)
		zf-H2C2_2	421..444	CDD:290200	19/22 (86%)
		zf-C2H2	434..456	CDD:278523	17/21 (81%)
		C2H2 Zn finger	436..456	CDD:275368	16/19 (84%)
		zf-H2C2_2	448..473	CDD:290200	16/24 (67%)
		C2H2 Zn finger	464..481	CDD:275368	10/16 (63%)
snai3	NP_001070853.1	C2H2 Zn finger	176..196	CDD:275368	16/19 (84%)
		C2H2 Zn finger	202..222	CDD:275368	17/19 (89%)
		zf-H2C2_2	215..238	CDD:290200	19/22 (86%)
		zf-C2H2	228..250	CDD:278523	17/21 (81%)
		C2H2 Zn finger	230..250	CDD:275368	16/19 (84%)
		C2H2 Zn finger	258..274	CDD:275368	9/15 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	47	1.000	Domainoid score	I12001
eggNOG	1	0.900	-	-		E1_KOG2462
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	231	1.000	Inparanoid score	I3419
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6484
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3546
SonicParanoid	1	1.000	-	-		X955
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	9	8.850