DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment wor and CG7691

DIOPT Version :9

Sequence 1:	NP_476601.1	Gene:	wor / 34906	FlyBaseID:	FBgn0001983	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	NP_650728.1	Gene:	CG7691 / 42228	FlyBaseID:	FBgn0038626	Length:	283	Species:	Drosophila melanogaster

Alignment Length:	383	Identity:	91/383 - (23%)
Similarity:	137/383 - (35%)	Gaps:	152/383 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly   144 PTIIKAEPSDEEQFPLRNYNNNLLKSIAEYED-CMKMQNIKEEIPPIPSPQLFY-------PPPT 200
            |.|.::..||       .||....:....||| |..:.|    :||:|.|:..:       |.|.
  Fly     2 PRIFRSFLSD-------RYNGKQERFYDRYEDFCQVIPN----LPPMPRPKTNHHSRVATKPEPK 55

  Fly   201 P---------LAEP-------EDLSVTQRRVLSENMNLQNVARALLSMQHMAPQHAPPPIDMEED 249
            .         .:||       :|:.:..||.:.|.:.:|     |:|:.         || .|..
  Fly    56 TNVKFTYCFGQSEPSGDWRQGDDIPIVVRREMEERLGIQ-----LMSVL---------PI-TESS 105

  Fly   250 QENQDINQLKI---------KSSNDLYYQCQQCNKCYATYAGLVKHQQTHAYESTEYKIIRSQPG 305
            ..:..|.:||:         |:.|.:             ..|::.       .:.|.|..|::..
  Fly   106 LLSHTIWELKMPGESFDSIPKTRNGI-------------KVGIIT-------VTAESKQTRTKLK 150

  Fly   306 GSGAIVDQTEFCTDQASALIQAANVASAQSMQKPVGVPRYHCQDCGKSYSTYSGLSKHQQFHCPS 370
            ..|.|:                |||....::   |.:|..                  ||...|
  Fly   151 RKGPIL----------------ANVTVPSNI---VEIPPI------------------QQRKMP- 177

  Fly   371 AEGNQVKKV---FSCKNCDKTYVSLGALKMHIRTHTLPCKCPICGKAFSRPWLLQGHIRTHTGEK 432
             |..::|:|   |.|.:||                          |.|...|:|..|.|||||||
  Fly   178 -EKRRLKRVGGQFECIDCD--------------------------KKFDHSWMLTAHTRTHTGEK 215

  Fly   433 PFSCQ--HCNRAFADRSNLRAHMQT--HSDVKKYSCPTCTKSFSRMSLLAKHLQSGCQ 486
            ||.|.  .|.:||:||||||:|.:|  |.: .::.|..|.|.||:.|.|.:|....|:
  Fly   216 PFVCPDGSCRKAFSDRSNLRSHQRTMGHHE-WQHQCGQCGKYFSQFSYLNRHSLDACR 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wor	NP_476601.1	C2H2 Zn finger	270..290	CDD:275368	1/19 (5%)
		C2H2 Zn finger	317..334	CDD:275368	3/16 (19%)
		zf-C2H2	345..367	CDD:278523	2/21 (10%)
		C2H2 Zn finger	347..367	CDD:275368	2/19 (11%)
		PHA00732	379..>417	CDD:177300	7/40 (18%)
		C2H2 Zn finger	382..402	CDD:275368	3/19 (16%)
		zf-C2H2_8	405..482	CDD:292531	35/80 (44%)
		zf-C2H2	406..428	CDD:278523	6/21 (29%)
		C2H2 Zn finger	408..428	CDD:275368	6/19 (32%)
		zf-H2C2_2	421..444	CDD:290200	14/24 (58%)
		zf-C2H2	434..456	CDD:278523	13/25 (52%)
		C2H2 Zn finger	436..456	CDD:275368	12/23 (52%)
		zf-H2C2_2	448..473	CDD:290200	10/26 (38%)
		C2H2 Zn finger	464..481	CDD:275368	7/16 (44%)
CG7691	NP_650728.1	COG5048	188..>271	CDD:227381	39/109 (36%)
		C2H2 Zn finger	191..211	CDD:275368	9/45 (20%)
		zf-H2C2_2	203..229	CDD:290200	14/25 (56%)
		C2H2 Zn finger	219..244	CDD:275368	12/24 (50%)
		C2H2 Zn finger	250..266	CDD:275368	7/15 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2462
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900