DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wor and snai2

DIOPT Version :9

Sequence 1:	NP_476601.1	Gene:	wor / 34906	FlyBaseID:	FBgn0001983	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	NP_989424.1	Gene:	snai2 / 395065	XenbaseID:	XB-GENE-487371	Length:	266	Species:	Xenopus tropicalis

Alignment Length:	341	Identity:	137/341 - (40%)
Similarity:	168/341 - (49%)	Gaps:	112/341 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   161 NY----NNNLLKSIAEYEDCMKMQNIKEEIPPIPSPQLF----YPPPT--------PLAEPEDLS 209
            ||    |:.::.|...||        :..:..:|.|:|:    |.|.|        ||  |.|||
Frog    18 NYGELDNHTVIISPFLYE--------RYPVSVLPQPELYSSVAYSPITVWTGLLHPPL--PSDLS 72

  Fly   210 VTQRRVLSENMNLQNVARALLSMQHMAPQHAPPPIDMEEDQENQDINQLKIKSSNDLYYQCQQCN 274
                              .|........:.:|||   :.|..::|
Frog    73 ------------------PLSGYPSSLGRVSPPP---QSDTSSKD-------------------- 96

  Fly   275 KCYATYAGLVKHQQTHAYESTEYKIIRSQPGGSGAIVDQTEFCTDQASALIQAANVASAQSMQKP 339
                           |:             |....|.|:.|             .:.:..|....
Frog    97 ---------------HS-------------GSESPISDEEE-------------RLQTKLSDSHA 120

  Fly   340 VGVPRYHCQDCGKSYSTYSGLSKHQQFHCPSAEGNQVKKVFSCKNCDKTYVSLGALKMHIRTHTL 404
            :...::.|..|.|:|||:|||:||:|.||.:    |.:|.||||.|:|.||||||||||||||||
Frog   121 IEAEKFQCSLCSKTYSTFSGLAKHKQLHCDA----QSRKSFSCKYCEKEYVSLGALKMHIRTHTL 181

  Fly   405 PCKCPICGKAFSRPWLLQGHIRTHTGEKPFSCQHCNRAFADRSNLRAHMQTHSDVKKYSCPTCTK 469
            ||.|.|||||||||||||||||||||||||||.|||||||||||||||:|||||||||.|..|:|
Frog   182 PCVCKICGKAFSRPWLLQGHIRTHTGEKPFSCPHCNRAFADRSNLRAHLQTHSDVKKYQCKNCSK 246

  Fly   470 SFSRMSLLAKHLQSGC 485
            :|||||||.||.:|||
Frog   247 TFSRMSLLHKHEESGC 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wor	NP_476601.1	C2H2 Zn finger	270..290	CDD:275368	0/19 (0%)
		C2H2 Zn finger	317..334	CDD:275368	0/16 (0%)
		zf-C2H2	345..367	CDD:278523	12/21 (57%)
		C2H2 Zn finger	347..367	CDD:275368	12/19 (63%)
		PHA00732	379..>417	CDD:177300	31/37 (84%)
		C2H2 Zn finger	382..402	CDD:275368	16/19 (84%)
		zf-C2H2_8	405..482	CDD:292531	66/76 (87%)
		zf-C2H2	406..428	CDD:278523	19/21 (90%)
		C2H2 Zn finger	408..428	CDD:275368	18/19 (95%)
		zf-H2C2_2	421..444	CDD:290200	21/22 (95%)
		zf-C2H2	434..456	CDD:278523	19/21 (90%)
		C2H2 Zn finger	436..456	CDD:275368	17/19 (89%)
		zf-H2C2_2	448..473	CDD:290200	18/24 (75%)
		C2H2 Zn finger	464..481	CDD:275368	11/16 (69%)
snai2	NP_989424.1	DUF4764	82..>160	CDD:292583	29/145 (20%)
		C2H2 Zn finger	128..148	CDD:275370	12/19 (63%)
		C2H2 Zn finger	159..179	CDD:275368	16/19 (84%)
		C2H2 Zn finger	185..205	CDD:275368	18/19 (95%)
		zf-H2C2_2	198..221	CDD:290200	21/22 (95%)
		zf-C2H2	211..233	CDD:278523	19/21 (90%)
		C2H2 Zn finger	213..233	CDD:275368	17/19 (89%)
		zf-H2C2_2	225..250	CDD:290200	18/24 (75%)
		C2H2 Zn finger	241..257	CDD:275368	10/15 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	52	1.000	Domainoid score	I11288
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	255	1.000	Inparanoid score	I3084
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9353
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3546
SonicParanoid	1	1.000	-	-		X955
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.990