DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wor and Scrt1

DIOPT Version :9

Sequence 1:	NP_476601.1	Gene:	wor / 34906	FlyBaseID:	FBgn0001983	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	NP_001124042.1	Gene:	Scrt1 / 366951	RGDID:	1306236	Length:	348	Species:	Rattus norvegicus

Alignment Length:	373	Identity:	117/373 - (31%)
Similarity:	158/373 - (42%)	Gaps:	103/373 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   138 YTRDASPTIIKAEPSDEEQFPLRNYNNNLLKSIAEYEDCMKMQNIKEEIPPIPSPQLFYPPPTPL 202
            |..||...::|. ||.|..:...                     ::.|:.|..|...  |||||
  Rat    51 YDGDAEAALLKG-PSPEPMYAAA---------------------VRGELGPAASGSA--PPPTP- 90

  Fly   203 AEPE-----------DLSVTQRRV-----LSENMNLQNVARALLSMQHMAPQHAPPPIDMEEDQE 251
             .||           |.:|::...     :::..:.:..|.|..:........|.|      |.:
  Rat    91 -RPELATAAGGYINGDAAVSEGYAADAFFITDGRSRRKAANANAASAPSTASVAAP------DSD 148

  Fly   252 NQDINQLKIKSSNDLYYQCQQCNKCYATYAGLVKHQQTHAYESTEYKIIRSQPGGSGAIVDQTEF 316
            .........:.|.                :|......|.....||   .|:.||.:||
  Rat   149 AGGGGGPGTRGSG----------------SGSASRGGTRVGAGTE---ARAGPGATGA------- 187

  Fly   317 CTDQASALIQAANVASAQSMQKPVGVPRYHCQDCGKSYSTYSGLSKHQQFHCPSAEGNQVKKVFS 381
                                     ..|:.|.:|||:|:|.|.||:|:|.| .|.:....::
  Rat   188 -------------------------GGRHACGECGKTYATSSNLSRHKQTH-RSLDSQLARR--- 223

  Fly   382 CKNCDKTYVSLGALKMHIRTHTLPCKCPICGKAFSRPWLLQGHIRTHTGEKPFSCQHCNRAFADR 446
            |..|.|.|||:.|:.||:.||.|..||.:||||||||||||||:|:|||||||.|.||.:|||||
  Rat   224 CPTCGKVYVSMPAMAMHLLTHDLRHKCGVCGKAFSRPWLLQGHMRSHTGEKPFGCAHCGKAFADR 288

  Fly   447 SNLRAHMQTHSDVKKYSCPTCTKSFSRMSLLAKHLQSGCQTEQSGGPS 494
            |||||||||||..|.:.|..|.|||:..|.|.||.:|.|....:.||:
  Rat   289 SNLRAHMQTHSAFKHFQCKRCKKSFALKSYLNKHYESACFKGGASGPA 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wor	NP_476601.1	C2H2 Zn finger	270..290	CDD:275368	1/19 (5%)
		C2H2 Zn finger	317..334	CDD:275368	0/16 (0%)
		zf-C2H2	345..367	CDD:278523	11/21 (52%)
		C2H2 Zn finger	347..367	CDD:275368	11/19 (58%)
		PHA00732	379..>417	CDD:177300	19/37 (51%)
		C2H2 Zn finger	382..402	CDD:275368	9/19 (47%)
		zf-C2H2_8	405..482	CDD:292531	53/76 (70%)
		zf-C2H2	406..428	CDD:278523	17/21 (81%)
		C2H2 Zn finger	408..428	CDD:275368	16/19 (84%)
		zf-H2C2_2	421..444	CDD:290200	16/22 (73%)
		zf-C2H2	434..456	CDD:278523	17/21 (81%)
		C2H2 Zn finger	436..456	CDD:275368	16/19 (84%)
		zf-H2C2_2	448..473	CDD:290200	16/24 (67%)
		C2H2 Zn finger	464..481	CDD:275368	8/16 (50%)
Scrt1	NP_001124042.1	C2H2 Zn finger	193..213	CDD:275368	11/19 (58%)
		C2H2 Zn finger	224..241	CDD:275371	8/16 (50%)
		COG5048	<245..>313	CDD:227381	48/67 (72%)
		C2H2 Zn finger	250..270	CDD:275368	16/19 (84%)
		C2H2 Zn finger	278..298	CDD:275368	16/19 (84%)
		C2H2 Zn finger	306..322	CDD:275368	7/15 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2462
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	179	1.000	Inparanoid score	I3910
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.860