DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wor and Scrt2

DIOPT Version :9

Sequence 1:	NP_476601.1	Gene:	wor / 34906	FlyBaseID:	FBgn0001983	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	NP_001178834.1	Gene:	Scrt2 / 366229	RGDID:	1564796	Length:	305	Species:	Rattus norvegicus

Alignment Length:	158	Identity:	87/158 - (55%)
Similarity:	106/158 - (67%)	Gaps:	8/158 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   341 GVPRYHCQDCGKSYSTYSGLSKHQQFHCPSAEGNQVKKVFSCKNCDKTYVSLGALKMHIRTHTLP 405
            |..|:.|.:|||:|:|.|.||:|:|.| .|.:....:|   |..|.|.|||:.||.||:.||.|.
  Rat   151 GGHRHACAECGKTYATSSNLSRHKQTH-RSLDSQLARK---CPTCGKAYVSMPALAMHVLTHNLR 211

  Fly   406 CKCPICGKAFSRPWLLQGHIRTHTGEKPFSCQHCNRAFADRSNLRAHMQTHSDVKKYSCPTCTKS 470
            .||.:||||||||||||||:|:|||||||.|.||.:||||||||||||||||..|.|.|..|.||
  Rat   212 HKCGVCGKAFSRPWLLQGHMRSHTGEKPFGCAHCGKAFADRSNLRAHMQTHSAFKHYRCRQCDKS 276

  Fly   471 FSRMSLLAKHLQSGC----QTEQSGGPS 494
            |:..|.|.||.::.|    :...|.||:
  Rat   277 FALKSYLHKHCEAACVKAAEPPPSAGPA 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wor	NP_476601.1	C2H2 Zn finger	270..290	CDD:275368
		C2H2 Zn finger	317..334	CDD:275368
		zf-C2H2	345..367	CDD:278523	11/21 (52%)
		C2H2 Zn finger	347..367	CDD:275368	11/19 (58%)
		PHA00732	379..>417	CDD:177300	20/37 (54%)
		C2H2 Zn finger	382..402	CDD:275368	10/19 (53%)
		zf-C2H2_8	405..482	CDD:292531	54/76 (71%)
		zf-C2H2	406..428	CDD:278523	17/21 (81%)
		C2H2 Zn finger	408..428	CDD:275368	16/19 (84%)
		zf-H2C2_2	421..444	CDD:290200	16/22 (73%)
		zf-C2H2	434..456	CDD:278523	17/21 (81%)
		C2H2 Zn finger	436..456	CDD:275368	16/19 (84%)
		zf-H2C2_2	448..473	CDD:290200	17/24 (71%)
		C2H2 Zn finger	464..481	CDD:275368	8/16 (50%)
Scrt2	NP_001178834.1	C2H2 Zn finger	157..177	CDD:275368	11/19 (58%)
		COG5048	<210..>277	CDD:227381	49/66 (74%)
		zf-C2H2	212..234	CDD:278523	17/21 (81%)
		C2H2 Zn finger	214..234	CDD:275368	16/19 (84%)
		zf-H2C2_2	227..250	CDD:290200	16/22 (73%)
		C2H2 Zn finger	242..262	CDD:275368	16/19 (84%)
		zf-C2H2	242..262	CDD:278523	16/19 (84%)
		zf-H2C2_2	254..278	CDD:290200	16/23 (70%)
		C2H2 Zn finger	270..286	CDD:275368	7/15 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2462
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	179	1.000	Inparanoid score	I3910
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.860