DRSC/TRiP Functional Genomics Resources

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Protein Alignment wor and az2

DIOPT Version :9

Sequence 1:NP_476601.1 Gene:wor / 34906 FlyBaseID:FBgn0001983 Length:548 Species:Drosophila melanogaster
Sequence 2:NP_610289.2 Gene:az2 / 35682 FlyBaseID:FBgn0025185 Length:593 Species:Drosophila melanogaster


Alignment Length:579 Identity:109/579 - (18%)
Similarity:183/579 - (31%) Gaps:211/579 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly    65 RRRFD------AAMNQTKEQLARRIWEE----TREIARAFPDV---FTREEIAKSLARLGYGEFE 116
            |..|:      |..|....::..:.|.|    .:|...|.|.:   .|..|:..| |:.   |.|
  Fly    10 RNNFEHFVLACAHQNDCYVEMEFKRWREFIVHVKEHLEANPSMQQELTTSEVISS-AKC---EEE 70

  Fly   117 LPPEEEVMEPEPEPEQHL--------PLRYTRDASPTIIKAEPSDEEQFPLRNYNNNLLKSIAEY 173
            :.|.:..:..|| ||..|        |.....|.|.:.::.|..::::          :.|.:..
  Fly    71 VSPAKVFIVEEP-PENCLAEDMFVDVPPSSENDESTSPVEEEEEEDDE----------VDSSSMT 124

  Fly   174 EDCMKMQNIKEEIPPIP---------SPQL-----FYPPPTPLAEPEDLSVTQRRVLSENMNLQN 224
            .||...........|:.         ||::     .|...|.|.:|.|.|...:.      ...|
  Fly   125 VDCELGTRNSTHFAPLTKFNPTFYRRSPRITQFIELYKQQTCLWDPADESYRDKE------KRAN 183

  Fly   225 VARALLSMQHMAPQHAPPPIDMEEDQENQDINQLKIKSSNDLYYQCQQCNKC----YATYAGLVK 285
            ....||.                           ::|::.:|:....:..||    :|.||.:.:
  Fly   184 AYEELLE---------------------------QLKATVNLHLTAYKLKKCITSLHAQYASISR 221

  Fly   286 HQQTH------AYESTEYKIIRSQPG----------GSGAI--------------VD-------- 312
            .::|.      .|...:|..:..:..          |.|.|              :|        
  Fly   222 QKKTQKLTKVPLYYHGKYSFLAERGSLEDADSDDVDGDGKIKLVFTEENQLTTQFIDLYSKFPQL 286

  Fly   313 ----QTEFC--TDQASALIQAANVA----------------SAQSMQ-------------KPVGV 342
                ...||  ..:.|:||:..::.                |.|||:             :.||:
  Fly   287 YDPAHKHFCNLNVRKSSLIEITDLLTSEFSLGLVTHYDVYDSIQSMRQWYSRRIKTLTDVQCVGL 351

  Fly   343 ---------------------PRYHCQDCGKSYSTYSGLSKHQ----------QFHCPSAEGN-- 374
                                 .:..|:.|..|:||...|..||          .|.|...|.|  
  Fly   352 SLAEKQYIERCNSFMPTKSFRQKLKCEVCEHSFSTDHALQAHQFRDHKMGDGGWFRCTLCELNFD 416

  Fly   375 ------------QVKKVFSCKNCDKTYVSLGALKMHIRTH-----TLPCKCPICGKAFSRPWLLQ 422
                        .:.|.|.|:.|.:::.....|.:|.|||     ..|..|..|||.|.:...:.
  Fly   417 RKCHLQQHSQRVHMDKSFVCEICSRSFAFGNQLAIHKRTHDEKHVAKPFVCEFCGKCFKQKIQMT 481

  Fly   423 GHI-RTHTGEKPFSCQHCNRAFADRSNLRAHMQTHSDVKKYSCPTCTKSFSRMSLLAKH 480
            .|: ..||..:.|.|..|.:.|..:.:|:.|::.|.:::...|..|.|:|:..:.|.||
  Fly   482 THVTAVHTKIRAFKCDMCPKDFLTKRDLKDHVKAHLNIRDKVCEVCQKAFTNANALVKH 540

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
worNP_476601.1 C2H2 Zn finger 270..290 CDD:275368 5/23 (22%)
C2H2 Zn finger 317..334 CDD:275368 5/34 (15%)
zf-C2H2 345..367 CDD:278523 8/31 (26%)
C2H2 Zn finger 347..367 CDD:275368 8/29 (28%)
PHA00732 379..>417 CDD:177300 14/42 (33%)
C2H2 Zn finger 382..402 CDD:275368 5/19 (26%)
zf-C2H2_8 405..482 CDD:292531 23/77 (30%)
zf-C2H2 406..428 CDD:278523 6/22 (27%)
C2H2 Zn finger 408..428 CDD:275368 6/20 (30%)
zf-H2C2_2 421..444 CDD:290200 6/23 (26%)
zf-C2H2 434..456 CDD:278523 6/21 (29%)
C2H2 Zn finger 436..456 CDD:275368 5/19 (26%)
zf-H2C2_2 448..473 CDD:290200 7/24 (29%)
C2H2 Zn finger 464..481 CDD:275368 7/17 (41%)
az2NP_610289.2 MADF_DNA_bdg 157..242 CDD:287510 19/117 (16%)
GT1 276..>341 CDD:304916 10/64 (16%)
C2H2 Zn finger 377..398 CDD:275368 8/20 (40%)
C2H2 Zn finger 408..429 CDD:275368 3/20 (15%)
C2H2 Zn finger 436..456 CDD:275368 5/19 (26%)
C2H2 Zn finger 467..488 CDD:275368 6/20 (30%)
C2H2 Zn finger 496..516 CDD:275368 5/19 (26%)
C2H2 Zn finger 524..544 CDD:275368 7/17 (41%)
C2H2 Zn finger 551..572 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR24409
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
11.100

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