DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wor and Cf2

DIOPT Version :9

Sequence 1:	NP_476601.1	Gene:	wor / 34906	FlyBaseID:	FBgn0001983	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	NP_001350854.1	Gene:	Cf2 / 33692	FlyBaseID:	FBgn0000286	Length:	537	Species:	Drosophila melanogaster

Alignment Length:	309	Identity:	81/309 - (26%)
Similarity:	123/309 - (39%)	Gaps:	71/309 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   183 KEEIPPIPSPQLFYPPPTPLAEPEDLSVTQRRVLSENMNLQNVARALLSMQHMAPQHAPPPIDME 247
            ::|....|..||      |...|.|:.:|...        |:..:.|.:..|...||      .:
  Fly   199 QQEAAVTPDDQL------PAMAPRDMRLTPEE--------QHHQQQLQAEHHHQQQH------QQ 243

  Fly   248 EDQENQDINQLKIKSSNDLYYQCQQ---------------------------CNKCYATYAGLVK 285
            :.|:.|...:|..:...::..|.||                           .|| .|....:|.
  Fly   244 QQQQQQQQQELLEQQQREMQEQAQQQQVHHHQQDQDLAGDQVALKVPPLTVKLNK-NANGGAIVS 307

  Fly   286 HQQTHAYESTEYKIIRSQP---GGSGAIVDQTEFCTDQASALIQAANVASAQSMQKPVGVP---- 343
            |.|.         ||:.:|   ..||.:|:.......||:..:.|.  ||:..:.....||
  Fly   308 HPQV---------IIKEEPLSLSDSGDVVNSVPVYAIQANPGVPAP--ASSGVLVGTQTVPADLA 361

  Fly   344 ---RYHCQDCGKSYSTYSGLSKHQQFHCPSAEGNQVKKVFSCKNCDKTYVSLGALKMHIRTHT-- 403
               |:.|.||.|::.|...|:.|::.|...|:....::.::|..|.|::.....||.|.|.||
  Fly   362 HKIRHKCPDCPKTFKTPGTLAMHRKIHTGEADATPKERPYTCSYCGKSFTQSNTLKQHTRIHTGE 426

  Fly   404 LPCKCPICGKAFSRPWLLQGHIRTHTGEKPFSCQHCNRAFADRSNLRAH 452
            .|..|..|.|:||....|..||||||||||::|.:|::.|..||.|..|
  Fly   427 KPFHCGYCEKSFSVKDYLTKHIRTHTGEKPYTCPYCDKRFTQRSALTVH 475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wor	NP_476601.1	C2H2 Zn finger	270..290	CDD:275368	8/46 (17%)
		C2H2 Zn finger	317..334	CDD:275368	5/16 (31%)
		zf-C2H2	345..367	CDD:278523	7/21 (33%)
		C2H2 Zn finger	347..367	CDD:275368	7/19 (37%)
		PHA00732	379..>417	CDD:177300	14/39 (36%)
		C2H2 Zn finger	382..402	CDD:275368	7/19 (37%)
		zf-C2H2_8	405..482	CDD:292531	24/48 (50%)
		zf-C2H2	406..428	CDD:278523	9/21 (43%)
		C2H2 Zn finger	408..428	CDD:275368	9/19 (47%)
		zf-H2C2_2	421..444	CDD:290200	13/22 (59%)
		zf-C2H2	434..456	CDD:278523	7/19 (37%)
		C2H2 Zn finger	436..456	CDD:275368	7/17 (41%)
		zf-H2C2_2	448..473	CDD:290200	2/5 (40%)
		C2H2 Zn finger	464..481	CDD:275368
Cf2	NP_001350854.1	COG5048	<366..>473	CDD:227381	40/106 (38%)
		C2H2 Zn finger	368..388	CDD:275368	7/19 (37%)
		C2H2 Zn finger	403..423	CDD:275368	7/19 (37%)
		C2H2 Zn finger	431..451	CDD:275368	9/19 (47%)
		zf-H2C2_2	443..468	CDD:316026	14/24 (58%)
		C2H2 Zn finger	459..480	CDD:275368	7/17 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457211
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	51	1.000	Inparanoid score	I2624
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.890