DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wor and snai-1

DIOPT Version :9

Sequence 1:	NP_476601.1	Gene:	wor / 34906	FlyBaseID:	FBgn0001983	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	NP_499902.2	Gene:	snai-1 / 186874	WormBaseID:	WBGene00019299	Length:	193	Species:	Caenorhabditis elegans

Alignment Length:	182	Identity:	94/182 - (51%)
Similarity:	121/182 - (66%)	Gaps:	21/182 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   327 AANVASAQSM--QKPVGVPRYHCQDCGKSYSTYSGLSKHQQFHCPSAEGNQVKKVFSCKNCDKTY 389
            :::.||..|:  ||.|      ||.|.|:|.||.||.:|.|||   .||   |...||.:|.|.|
Worm    27 SSSSASCSSLDNQKLV------CQFCKKTYLTYFGLRRHLQFH---KEG---KLQQSCPHCKKVY 79

  Fly   390 VSLGALKMHIRTHTLPCKCPICGKAFSRPWLLQGHIRTHTGEKPFSCQHCNRAFADRSNLRAHMQ 454
            .|.||||||::||:|||.|..|||:|||||||:||:|||||||||.|:.|.|.||||||||||:|
Worm    80 RSPGALKMHLKTHSLPCVCNDCGKSFSRPWLLKGHLRTHTGEKPFGCEFCGRCFADRSNLRAHLQ 144

  Fly   455 THSDVKKYSCPTCTKSFSRMSLLAKHLQSGCQTEQSGGPSGSGGGFDQQQLQ 506
            |||..||:.|..|.:||:|:.:..:|.|. |:    ||  ||||..:::.::
Worm   145 THSGEKKHRCSRCGQSFARVQVRQRHEQC-CR----GG--GSGGEAEKEDVE 189

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wor	NP_476601.1	C2H2 Zn finger	270..290	CDD:275368
		C2H2 Zn finger	317..334	CDD:275368	2/6 (33%)
		zf-C2H2	345..367	CDD:278523	11/21 (52%)
		C2H2 Zn finger	347..367	CDD:275368	11/19 (58%)
		PHA00732	379..>417	CDD:177300	22/37 (59%)
		C2H2 Zn finger	382..402	CDD:275368	11/19 (58%)
		zf-C2H2_8	405..482	CDD:292531	49/76 (64%)
		zf-C2H2	406..428	CDD:278523	15/21 (71%)
		C2H2 Zn finger	408..428	CDD:275368	14/19 (74%)
		zf-H2C2_2	421..444	CDD:290200	15/22 (68%)
		zf-C2H2	434..456	CDD:278523	15/21 (71%)
		C2H2 Zn finger	436..456	CDD:275368	14/19 (74%)
		zf-H2C2_2	448..473	CDD:290200	15/24 (63%)
		C2H2 Zn finger	464..481	CDD:275368	5/16 (31%)
snai-1	NP_499902.2	C2H2 Zn finger	72..92	CDD:275368	11/19 (58%)
		COG5048	98..>155	CDD:227381	41/56 (73%)
		C2H2 Zn finger	98..118	CDD:275368	14/19 (74%)
		C2H2 Zn finger	126..146	CDD:275368	14/19 (74%)
		zf-H2C2_2	138..163	CDD:290200	15/24 (63%)
		C2H2 Zn finger	154..170	CDD:275368	5/15 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I8191
eggNOG	1	0.900	-	-		E1_KOG2462
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14747
orthoMCL	1	0.900	-	-		OOG6_107394
Panther	1	1.100	-	-	LDO	PTHR24409
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3546
SonicParanoid	1	1.000	-	-		X955
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	9.800