DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wor and LOC110437726

DIOPT Version :9

Sequence 1:	NP_476601.1	Gene:	wor / 34906	FlyBaseID:	FBgn0001983	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	XP_021331500.1	Gene:	LOC110437726 / 110437726	-ID:	-	Length:	550	Species:	Danio rerio

Alignment Length:	350	Identity:	97/350 - (27%)
Similarity:	150/350 - (42%)	Gaps:	55/350 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   168 KSIAEYEDCMKMQNIKEEIPPIPSPQLFYPPPTPLAEPEDLSVTQRRVLSENMNLQNVARALLSM 232
            ||..:.::|.....|.....|....|.            |:..||:..|:.:|.: :......:.
Zfish   109 KSFNQKQNCEAHMRIHTGEKPYKCQQC------------DMQFTQKANLTVHMRV-HTGEKTFNC 160

  Fly   233 QHMAPQHAPPPIDMEEDQENQDINQLKIKSSNDLYYQCQQCNKCYATYAGLVKHQQTHAYESTEY 297
            ||......          :.|::|......:.:..||||||.|.::....|..|.:.|..|
Zfish   161 QHCGKSFF----------QKQNLNVHMRVHTGEKPYQCQQCGKSFSQPQNLNVHLKVHTGE---- 211

  Fly   298 KIIRSQPGGSGAIVDQTEFCTDQASALIQAANVASAQSMQKPVGVPRYHCQDCGKSYSTYSGLSK 362
            |....|..|. :.:.:.:|                ...|:...|...|.|..||||:|..:.|..
Zfish   212 KPFTCQECGK-SFIHKQKF----------------EAHMRIHTGEKLYKCLQCGKSFSQKTYLED 259

  Fly   363 HQQFHCPSAEGNQVKKVFSCKNCDKTYVSLGALKMHIRTHT--LPCKCPICGKAFSRPWLLQGHI 425
            |...|   ||    .|.|||:.|.|::.....||||:|.||  .|..|..||::||:...|:.|:
Zfish   260 HMGIH---AE----VKPFSCQQCGKSFNQKQKLKMHMRVHTGEKPYSCQHCGRSFSQAPSLEVHM 317

  Fly   426 RTHTGEKPFSCQHCNRAFADRSNLRAHMQTHSDVKKYSCPTCTKSFSRMSLLAKHLQSGCQTEQS 490
            |.||||||::|..|.:.||.:.:|..|.:.|:..|.|:|..|..||::.|.|.:||:...:.:..
Zfish   318 RVHTGEKPYTCDQCGKTFAQKGHLDKHTRVHTGEKPYTCDLCGISFAQKSNLNRHLKIHTKEKPY 382

  Fly   491 GGPSGSGGGFDQQ-QLQQHLQVYEE 514
            ..|. .|..|.|: .||:|:.::.|
Zfish   383 MCPQ-CGKSFIQKVTLQEHMNIHRE 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wor	NP_476601.1	C2H2 Zn finger	270..290	CDD:275368	7/19 (37%)
		C2H2 Zn finger	317..334	CDD:275368	0/16 (0%)
		zf-C2H2	345..367	CDD:278523	9/21 (43%)
		C2H2 Zn finger	347..367	CDD:275368	8/19 (42%)
		PHA00732	379..>417	CDD:177300	17/39 (44%)
		C2H2 Zn finger	382..402	CDD:275368	8/19 (42%)
		zf-C2H2_8	405..482	CDD:292531	31/76 (41%)
		zf-C2H2	406..428	CDD:278523	8/21 (38%)
		C2H2 Zn finger	408..428	CDD:275368	8/19 (42%)
		zf-H2C2_2	421..444	CDD:290200	11/22 (50%)
		zf-C2H2	434..456	CDD:278523	6/21 (29%)
		C2H2 Zn finger	436..456	CDD:275368	6/19 (32%)
		zf-H2C2_2	448..473	CDD:290200	9/24 (38%)
		C2H2 Zn finger	464..481	CDD:275368	6/16 (38%)
LOC110437726	XP_021331500.1	COG5048	73..485	CDD:227381	96/349 (28%)
		C2H2 Zn finger	76..96	CDD:275368
		C2H2 Zn finger	104..124	CDD:275368	3/14 (21%)
		C2H2 Zn finger	132..152	CDD:275368	6/32 (19%)
		C2H2 Zn finger	160..180	CDD:275368	4/29 (14%)
		C2H2 Zn finger	188..208	CDD:275368	7/19 (37%)
		C2H2 Zn finger	216..236	CDD:275368	4/36 (11%)
		C2H2 Zn finger	244..264	CDD:275368	8/19 (42%)
		C2H2 Zn finger	272..292	CDD:275368	8/19 (42%)
		C2H2 Zn finger	300..320	CDD:275368	8/19 (42%)
		C2H2 Zn finger	328..348	CDD:275368	6/19 (32%)
		C2H2 Zn finger	356..376	CDD:275368	8/19 (42%)
		C2H2 Zn finger	384..404	CDD:275368	7/20 (35%)
		C2H2 Zn finger	412..432	CDD:275368
		C2H2 Zn finger	440..460	CDD:275368
		C2H2 Zn finger	468..488	CDD:275368
		C2H2 Zn finger	496..514	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910