DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wor and LOC101886047

DIOPT Version :9

Sequence 1:	NP_476601.1	Gene:	wor / 34906	FlyBaseID:	FBgn0001983	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	XP_005171139.1	Gene:	LOC101886047 / 101886047	-ID:	-	Length:	483	Species:	Danio rerio

Alignment Length:	349	Identity:	95/349 - (27%)
Similarity:	135/349 - (38%)	Gaps:	101/349 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   177 MKMQNIKEEIPPIPSPQLFYPPPTPLAEPEDLSVTQRRVLSENMNLQNVARALLSMQHMAPQHAP 241
            :||::||||                 .|..:....:.....|.::|..|            :...
Zfish     3 IKMESIKEE-----------------TEDAETHTVKEEENEEQIDLMRV------------KEET 38

  Fly   242 PPIDMEEDQENQDIN-------------QLKIKSSNDLYYQCQQCNKCYATYAGLVKHQQTHAYE 293
            |.: ||..:|.||.|             ::.::.|.|..|.|.||.|.:.....|..|..||.
Zfish    39 PDL-MEVKEEGQDQNPLDSPITEVKTEQKIHLEQSTDRPYACDQCGKRFTLKKCLKSHINTHT-- 100

  Fly   294 STEYKIIRSQPGGSGAIVDQTEFCTDQASALIQAANVASAQSMQKPVGVPRYHCQDCGKSYSTYS 358
                       |......||.|.|....|:|.:...:.|.   :||     :.|..||:.::..:
Zfish   101 -----------GNKPYACDQCEKCFTAQSSLERHMLIHSG---EKP-----FKCDQCGRRFTYKN 146

  Fly   359 GLSKHQQFHCPSAEGNQVKKVFSCKNCDKTYVSLGALKMHIRTHT--LPCKCPICGKAFSRPWLL 421
            .|..|:  :|.|.|     |.|.|..|.|::.....||.||:||:  .|..|..|||:|.....:
Zfish   147 DLKIHK--YCHSGE-----KPFRCTQCGKSFTLKKTLKSHIKTHSQNKPYTCDRCGKSFIYQSSI 204

  Fly   422 QGHIRTHTGEKPFSCQHCNRAFADRSNLRAHMQTHSDVKKYSCP--------------------- 465
            :.|:|.|||||||.|..|.::|.|:.|||.|||.||.:...|||
Zfish   205 ERHMRIHTGEKPFQCDQCGKSFIDKVNLRNHMQIHSGLNSVSCPQCGNILRSKAHLKIHMRIHTG 269

  Fly   466 -------TCTKSFSRMSLLAKHLQ 482
                   .|.|||||...|..|::
Zfish   270 ERPYVCVQCGKSFSRSGALKIHMR 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wor	NP_476601.1	C2H2 Zn finger	270..290	CDD:275368	6/19 (32%)
		C2H2 Zn finger	317..334	CDD:275368	4/16 (25%)
		zf-C2H2	345..367	CDD:278523	5/21 (24%)
		C2H2 Zn finger	347..367	CDD:275368	5/19 (26%)
		PHA00732	379..>417	CDD:177300	16/39 (41%)
		C2H2 Zn finger	382..402	CDD:275368	7/19 (37%)
		zf-C2H2_8	405..482	CDD:292531	38/104 (37%)
		zf-C2H2	406..428	CDD:278523	7/21 (33%)
		C2H2 Zn finger	408..428	CDD:275368	7/19 (37%)
		zf-H2C2_2	421..444	CDD:290200	11/22 (50%)
		zf-C2H2	434..456	CDD:278523	11/21 (52%)
		C2H2 Zn finger	436..456	CDD:275368	10/19 (53%)
		zf-H2C2_2	448..473	CDD:290200	15/52 (29%)
		C2H2 Zn finger	464..481	CDD:275368	9/44 (20%)
LOC101886047	XP_005171139.1	Merozoite_SPAM	<4..98	CDD:284533	26/123 (21%)
		COG5048	69..410	CDD:227381	78/253 (31%)
		C2H2 Zn finger	79..99	CDD:275368	6/19 (32%)
		C2H2 Zn finger	107..127	CDD:275368	6/19 (32%)
		zf-H2C2_2	119..144	CDD:290200	7/32 (22%)
		C2H2 Zn finger	135..155	CDD:275368	5/21 (24%)
		zf-H2C2_2	147..171	CDD:290200	10/30 (33%)
		C2H2 Zn finger	163..183	CDD:275368	7/19 (37%)
		C2H2 Zn finger	191..211	CDD:275368	7/19 (37%)
		zf-H2C2_2	203..226	CDD:290200	11/22 (50%)
		C2H2 Zn finger	219..267	CDD:275368	15/47 (32%)
		zf-H2C2_2	259..284	CDD:290200	4/24 (17%)
		C2H2 Zn finger	275..295	CDD:275368	8/19 (42%)
		zf-H2C2_2	287..312	CDD:290200	2/7 (29%)
		C2H2 Zn finger	303..323	CDD:275368
		C2H2 Zn finger	331..349	CDD:275368
		C2H2 Zn finger	356..376	CDD:275368
		C2H2 Zn finger	384..404	CDD:275368
		C2H2 Zn finger	426..445	CDD:275368
		C2H2 Zn finger	453..473	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910