DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wor and LOC101885996

DIOPT Version :9

Sequence 1:	NP_476601.1	Gene:	wor / 34906	FlyBaseID:	FBgn0001983	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	XP_005165065.1	Gene:	LOC101885996 / 101885996	-ID:	-	Length:	537	Species:	Danio rerio

Alignment Length:	361	Identity:	91/361 - (25%)
Similarity:	144/361 - (39%)	Gaps:	78/361 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   204 EPEDLSVTQRRVLSENMNLQNVARALLSMQHMAPQHAPPPIDMEEDQENQDINQLKIK------- 261
            |.||:.:....|..|:...:..|                   ||..:||:.:||.:.|
Zfish     7 ESEDMKIIAVTVKDEDAEEETDA-------------------MEMKEENEALNQAEEKYEYGKRR 52

  Fly   262 ----------------SSN--------DLYYQCQQCNKCYATYAGLVKHQQTHAYE--------- 293
                            |:|        :..:.|:||.:.:...|.|..|.:||..|
Zfish    53 GFVTGENSFSCPQLTDSANREPTTTRVEKPFTCEQCGRGFLKNATLKGHMRTHTGEKPFSCQQCG 117

  Fly   294 ---STEYKIIRSQPGGSGAIVDQTEFCTDQASALIQAANVASAQSMQKPVGVPRYHCQDCGKSYS 355
               |.:..:.|.|...:|   ::...||.........||:  ...|....|:..:.|:.||||:.
Zfish   118 SSFSQKGTLTRHQRVHTG---EKPYTCTLCGKGFTAVANL--TYHMNIHAGLKPFTCEQCGKSFR 177

  Fly   356 TYSGLSKHQQFHCPSAEGNQVKKVFSCKNCDKTYVSLGALKMHIRTHT--LPCKCPICGKAFSRP 418
            ....||.|.:.|  |.|     ..|.|..|.:::.::..|..|::.|:  ....|.:|.|:|...
Zfish   178 RKKTLSCHMKVH--SRE-----DCFICHQCGRSFPNIKCLDTHVKIHSGEKLFDCQLCEKSFRFK 235

  Fly   419 WLLQGHIRTHTGEKPFSCQHCNRAFADRSNLRAHMQTHSDVKKYSCPTCTKSFSRMSLLAKHLQS 483
            ..|:.|:|.||||||::|.||.:.|....:|:.||:.||..|.|:|..|.|||...:.|..|::.
Zfish   236 VGLKSHMRIHTGEKPYTCCHCGKDFRFSVSLKTHMRLHSGEKPYACSQCGKSFKYKATLNAHMRG 300

  Fly   484 GCQTEQSGGPSGSGGGFDQQ-QLQQHLQVYEEGHNP 518
            ....|........|..|.|: .|:.|::|: .|..|
Zfish   301 HTGEESPHVCKLCGNSFSQKGNLKIHMRVH-TGEKP 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wor	NP_476601.1	C2H2 Zn finger	270..290	CDD:275368	6/19 (32%)
		C2H2 Zn finger	317..334	CDD:275368	4/16 (25%)
		zf-C2H2	345..367	CDD:278523	8/21 (38%)
		C2H2 Zn finger	347..367	CDD:275368	8/19 (42%)
		PHA00732	379..>417	CDD:177300	10/39 (26%)
		C2H2 Zn finger	382..402	CDD:275368	4/19 (21%)
		zf-C2H2_8	405..482	CDD:292531	31/76 (41%)
		zf-C2H2	406..428	CDD:278523	7/21 (33%)
		C2H2 Zn finger	408..428	CDD:275368	7/19 (37%)
		zf-H2C2_2	421..444	CDD:290200	12/22 (55%)
		zf-C2H2	434..456	CDD:278523	7/21 (33%)
		C2H2 Zn finger	436..456	CDD:275368	7/19 (37%)
		zf-H2C2_2	448..473	CDD:290200	12/24 (50%)
		C2H2 Zn finger	464..481	CDD:275368	6/16 (38%)
LOC101885996	XP_005165065.1	COG5048	54..518	CDD:227381	78/295 (26%)
		C2H2 Zn finger	85..105	CDD:275368	6/19 (32%)
		zf-H2C2_2	98..122	CDD:290200	5/23 (22%)
		C2H2 Zn finger	113..133	CDD:275368	3/19 (16%)
		zf-H2C2_2	126..149	CDD:290200	5/25 (20%)
		C2H2 Zn finger	141..161	CDD:275368	5/21 (24%)
		C2H2 Zn finger	169..189	CDD:275368	8/19 (42%)
		C2H2 Zn finger	197..217	CDD:275368	4/19 (21%)
		C2H2 Zn finger	225..245	CDD:275368	7/19 (37%)
		zf-H2C2_2	238..260	CDD:290200	12/21 (57%)
		C2H2 Zn finger	253..273	CDD:275368	7/19 (37%)
		zf-H2C2_2	265..290	CDD:290200	12/24 (50%)
		C2H2 Zn finger	281..301	CDD:275368	7/19 (37%)
		C2H2 Zn finger	310..330	CDD:275368	5/19 (26%)
		zf-H2C2_2	322..347	CDD:290200	5/15 (33%)
		C2H2 Zn finger	338..358	CDD:275368
		C2H2 Zn finger	366..386	CDD:275368
		C2H2 Zn finger	394..414	CDD:275368
		C2H2 Zn finger	422..442	CDD:275368
		C2H2 Zn finger	477..497	CDD:275368
		C2H2 Zn finger	505..522	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910