DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wor and znf982

DIOPT Version :9

Sequence 1:	NP_476601.1	Gene:	wor / 34906	FlyBaseID:	FBgn0001983	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	XP_017207343.2	Gene:	znf982 / 100331424	ZFINID:	ZDB-GENE-131120-1	Length:	600	Species:	Danio rerio

Alignment Length:	501	Identity:	124/501 - (24%)
Similarity:	196/501 - (39%)	Gaps:	125/501 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 QPVPTELRRRFD-AAMNQTKEQLARRIWEETREIARAFPDVFTREEIAKSLARLGYGEFELPPEE 121
            ||....:|||.. |||...   |.|....|:.|::.....:...:.:.|:             .|
Zfish    32 QPPIKLVRRRIRVAAMTSA---LTRSFSVESTELSSVPSSLKDEDSLLKN-------------SE 80

  Fly   122 EVMEPEPEPEQHLPLRYTRDASPTIIKAEPSDEE---QFPLRNYNNNLLKSIAEYEDCMKMQNIK 183
            ::.:||                |.:||.|.::||   ..|::: .:.|||      |..||.:
Zfish    81 KMSDPE----------------PCLIKQEDTEEEIALPPPVKD-EDGLLK------DSEKMSD-- 120

  Fly   184 EEIPPIPSPQLFYPPPTPLAEPEDLSVTQRRVLSENMNLQNVARALLSMQHMAPQHA----PPPI 244
                    |:|:........|..||.|.:|.||||:.....|...:.|  |...:|:    .|.|
Zfish   121 --------PELYQIKQEETEEQIDLIVEEREVLSEDEEKHRVKGEIES--HTKTEHSLLLKRPAI 175

  Fly   245 D-------MEEDQENQDINQLKIKSSNDLYYQCQQCNKCYATYAGLVKHQQTHAYES-------- 294
            .       .:......|:|......:.:..|:|..|:|.:.....|..|::.|..|.
Zfish   176 KAFTCTRCAKSFSYKCDLNHHIRIHNGEKPYKCSHCDKRFNRSGHLKTHERIHTGEKPYTCDQCG 240

  Fly   295 ---------TEYKIIRSQPGGSGAIVDQTEFCTDQASALIQAANVASAQSMQKPVGVPRYH-CQD 349
                     .::.||.:.        ::|..|...:...:..:.:.....:.|  ...:.| |.:
Zfish   241 KSFVQISHLNQHMIIHNG--------EKTYTCDQCSKTFLVYSELKDHLKVHK--NETKSHTCPE 295

  Fly   350 CGKSYSTYSGLSKHQQFHCPSAEGNQVKKVFSCKNCDKTYVSLGALKMHIRTHT--LPCKCPICG 412
            |||::..:|.|.|||:.|....|       :.|..|:||:::.|.||.|.:.||  .|..|..|.
Zfish   296 CGKNFIWHSSLKKHQKIHTGVRE-------YMCSECEKTFITSGDLKQHQKIHTGEKPYMCSHCN 353

  Fly   413 KAFSRPWLLQGHIRTHTGEKPFSCQHCNRAFADRSNLRAHMQTHSDVKKYSCPTCTKSFSRMSLL 477
            |.||....|:.|.|.||||||::|..|.::|...::|..||..|:..|.:.|..|.|:|.|.|.|
Zfish   354 KRFSHVKPLKVHERIHTGEKPYTCTQCGKSFRQSAHLNEHMLIHNGEKTHKCDHCGKTFLRPSEL 418

  Fly   478 AKHLQ----------SGCQTEQSGGPSGSGGGFDQQ-QLQQHLQVY 512
            .|||:          |.|:.           .|.|| .|.||.:::
Zfish   419 KKHLRVHTKEKPYSCSVCEK-----------SFTQQSHLSQHQKIH 453

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wor	NP_476601.1	C2H2 Zn finger	270..290	CDD:275368	5/19 (26%)
		C2H2 Zn finger	317..334	CDD:275368	1/16 (6%)
		zf-C2H2	345..367	CDD:278523	10/22 (45%)
		C2H2 Zn finger	347..367	CDD:275368	9/19 (47%)
		PHA00732	379..>417	CDD:177300	15/39 (38%)
		C2H2 Zn finger	382..402	CDD:275368	8/19 (42%)
		zf-C2H2_8	405..482	CDD:292531	32/76 (42%)
		zf-C2H2	406..428	CDD:278523	8/21 (38%)
		C2H2 Zn finger	408..428	CDD:275368	8/19 (42%)
		zf-H2C2_2	421..444	CDD:290200	11/22 (50%)
		zf-C2H2	434..456	CDD:278523	6/21 (29%)
		C2H2 Zn finger	436..456	CDD:275368	6/19 (32%)
		zf-H2C2_2	448..473	CDD:290200	9/24 (38%)
		C2H2 Zn finger	464..481	CDD:275368	8/16 (50%)
znf982	XP_017207343.2	C2H2 Zn finger	180..200	CDD:275368	2/19 (11%)
		COG5048	204..537	CDD:227381	76/278 (27%)
		C2H2 Zn finger	208..228	CDD:275368	5/19 (26%)
		C2H2 Zn finger	236..256	CDD:275368	1/19 (5%)
		C2H2 Zn finger	264..284	CDD:275368	1/19 (5%)
		C2H2 Zn finger	293..313	CDD:275368	9/19 (47%)
		C2H2 Zn finger	321..341	CDD:275368	8/19 (42%)
		C2H2 Zn finger	349..369	CDD:275368	8/19 (42%)
		C2H2 Zn finger	377..397	CDD:275368	6/19 (32%)
		C2H2 Zn finger	405..425	CDD:275368	10/19 (53%)
		C2H2 Zn finger	433..453	CDD:275368	8/30 (27%)
		C2H2 Zn finger	461..481	CDD:275368
		C2H2 Zn finger	489..509	CDD:275368
		C2H2 Zn finger	517..537	CDD:275368
		zf-H2C2_2	529..554	CDD:316026
		C2H2 Zn finger	545..565	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910