DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wor and si:ch73-40a17.4

DIOPT Version :9

Sequence 1:	NP_476601.1	Gene:	wor / 34906	FlyBaseID:	FBgn0001983	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	XP_005171145.1	Gene:	si:ch73-40a17.4 / 100149710	ZFINID:	ZDB-GENE-131127-71	Length:	408	Species:	Danio rerio

Alignment Length:	449	Identity:	103/449 - (22%)
Similarity:	156/449 - (34%)	Gaps:	138/449 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   121 EEVMEPEPEPEQHLPLRYTRDASPTIIKAEPSDEEQFPLRNYNNNLLKSIAEYEDCMKMQNIKEE 185
            |:..:.|.:.|:|..:...:|.     ..||.:.|.....|..|       |.:.|...:|..:
Zfish     9 EDKSDAEQDAEEHKGMMEVKDE-----HKEPEEAEMNEQMNITN-------EEQSCSSSRNDNQ- 60

  Fly   186 IPPIPSPQLFYPPPTPLAEPED----------LSVTQRRVLSENMNLQNVARALLSMQ------- 233
                          ...||.:.          .|.|:|..|..:|.:....|....:|
Zfish    61 --------------VSQAETQSKHSFICSECGKSFTRRGHLRIHMIIHTGERPYTCIQCQKSFTC 111

  Fly   234 ----------------HMAPQHAPPPIDMEEDQENQDINQLKIKSSNDLYYQCQQCNKCYATYAG 282
                            .|.|| .......:||.:    ..::| .:.:..:.|.||.|.:.:...
Zfish   112 KGSLKDHCKIHSGEKPFMCPQ-CGWSFARQEDLK----RHIRI-HTGEKPFSCAQCTKSFTSSGD 170

  Fly   283 LVKHQQTHAYESTEYKIIRSQPGGSGAIVDQTEFCTDQASALIQAANVASAQSMQKPVGVPRYHC 347
            |.:|.:.|:.|         :|....    |.:....|...|.:.|.:.|.:.:        :.|
Zfish   171 LRRHVRIHSGE---------RPFSCA----QCKKSFTQKEGLKEHAKIHSGEKL--------FAC 214

  Fly   348 QDCGKSYSTYSGLSKHQQFH-------CPS-----AEGNQVK---------KVFSCKNCDKTYVS 391
            ..||||::....|.:|.:.|       ||.     ||...:|         :.|||:.|:|.:..
Zfish   215 MLCGKSFTHQRSLKRHMKVHSGEKLHQCPECGRRFAEAGNLKTHLLSHTGERPFSCEKCEKKFFL 279

  Fly   392 LGALKMHIRTH------------------------------TLPCKCPICGKAFSRPWLLQGHIR 426
            ...||.|:|.|                              ..|..|..||..|.||..|:.|.|
Zfish   280 AVHLKTHMRIHEDERRYVCSFCGKSFLWLNGFKDHQKTHIGEKPYVCLECGSTFIRPGELKVHER 344

  Fly   427 THTGEKPFSCQHCNRAFADRSNLRAHMQTHSDVKKYSCPTCTKSFSRMSLLAKHLQSGC 485
            .||||||:.|.||.::|.....|:.|.:.|:..|.|.||||.|:|||...|.|||:..|
Zfish   345 IHTGEKPYKCSHCEKSFTQSGALKIHKRVHTGEKPYLCPTCGKTFSRYGNLGKHLKKAC 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wor	NP_476601.1	C2H2 Zn finger	270..290	CDD:275368	6/19 (32%)
		C2H2 Zn finger	317..334	CDD:275368	4/16 (25%)
		zf-C2H2	345..367	CDD:278523	7/21 (33%)
		C2H2 Zn finger	347..367	CDD:275368	7/19 (37%)
		PHA00732	379..>417	CDD:177300	15/67 (22%)
		C2H2 Zn finger	382..402	CDD:275368	7/19 (37%)
		zf-C2H2_8	405..482	CDD:292531	36/76 (47%)
		zf-C2H2	406..428	CDD:278523	9/21 (43%)
		C2H2 Zn finger	408..428	CDD:275368	9/19 (47%)
		zf-H2C2_2	421..444	CDD:290200	12/22 (55%)
		zf-C2H2	434..456	CDD:278523	6/21 (29%)
		C2H2 Zn finger	436..456	CDD:275368	6/19 (32%)
		zf-H2C2_2	448..473	CDD:290200	11/24 (46%)
		C2H2 Zn finger	464..481	CDD:275368	10/16 (63%)
si:ch73-40a17.4	XP_005171145.1	COG5048	<40..193	CDD:227381	30/193 (16%)
		C2H2 Zn finger	74..94	CDD:275368	5/19 (26%)
		zf-H2C2_2	86..111	CDD:290200	4/24 (17%)
		C2H2 Zn finger	102..122	CDD:275368	1/19 (5%)
		C2H2 Zn finger	130..150	CDD:275368	5/25 (20%)
		zf-H2C2_2	142..167	CDD:290200	6/29 (21%)
		zf-C2H2_8	155..235	CDD:292531	21/100 (21%)
		C2H2 Zn finger	158..178	CDD:275368	6/19 (32%)
		zf-H2C2_2	170..195	CDD:290200	6/37 (16%)
		C2H2 Zn finger	186..206	CDD:275368	4/23 (17%)
		C2H2 Zn finger	214..234	CDD:275368	7/19 (37%)
		zf-H2C2_2	226..250	CDD:290200	5/23 (22%)
		C2H2 Zn finger	242..262	CDD:275368	5/19 (26%)
		C2H2 Zn finger	270..290	CDD:275368	7/19 (37%)
		C2H2 Zn finger	298..318	CDD:275368	0/19 (0%)
		C2H2 Zn finger	326..346	CDD:275368	9/19 (47%)
		zf-H2C2_2	338..363	CDD:290200	13/24 (54%)
		C2H2 Zn finger	354..374	CDD:275368	6/19 (32%)
		zf-H2C2_2	366..391	CDD:290200	11/24 (46%)
		C2H2 Zn finger	382..400	CDD:275368	11/17 (65%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910