DRSC/TRiP Functional Genomics Resources

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Protein Alignment esg and SCRT2

DIOPT Version :9

Sequence 1:NP_476600.1 Gene:esg / 34903 FlyBaseID:FBgn0001981 Length:470 Species:Drosophila melanogaster
Sequence 2:NP_149120.1 Gene:SCRT2 / 85508 HGNCID:15952 Length:307 Species:Homo sapiens


Alignment Length:351 Identity:120/351 - (34%)
Similarity:154/351 - (43%) Gaps:75/351 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   120 VPTPTYPKYPWNNFHMSPYTAEFYRTINQQGHQILPLRGDLIAPSSPSDSLGSLSPPPHHYLHGR 184
            ||.|||                         |   ||....:.|       |:..||..   :|.
Human    20 VPAPTY-------------------------H---PLETAYVLP-------GARGPPGD---NGY 46

  Fly   185 ASSVSPPMRSEIIHRPIGVRQHRFLPYPQMPGYPSLGGYTHTHHHHAPISP-AYSE----NSYYS 244
            |....||...:...:| |:..     .|..|.||             |.:| .||:    .|..|
Human    47 APHRLPPSSYDADQKP-GLEL-----APAEPAYP-------------PAAPEEYSDPESPQSSLS 92

  Fly   245 MRSMTPESSCSSSLPEDLSLKHKNLNLNLNTSQPGEQAAAKTGDMSPETMPNASAKKDKNQPPRY 309
            .|....|::.:.|...|........:........|:  |..:||..........|........|:
Human    93 ARYFRGEAAVTDSYSMDAFFISDGRSRRRRGGGGGD--AGGSGDAGGAGGRAGRAGAQAGGGHRH 155

  Fly   310 QCPDCQKSYSTFSGLTKHQQFHCPAAEGNQVKKSFSCKDCDKTYVSLGALKMHIRTHTLPCKCNL 374
            .|.:|.|:|:|.|.|::|:|.| .:.:....:|   |..|.|.|||:.||.||:.||.|..||.:
Human   156 ACAECGKTYATSSNLSRHKQTH-RSLDSQLARK---CPTCGKAYVSMPALAMHLLTHNLRHKCGV 216

  Fly   375 CGKAFSRPWLLQGHIRTHTGEKPFSCQHCHRAFADRSNLRAHLQTHSDIKKYSCTSCSKTFSRMS 439
            ||||||||||||||:|:|||||||.|.||.:|||||||||||:||||..|.|.|..|.|:|:..|
Human   217 CGKAFSRPWLLQGHMRSHTGEKPFGCAHCGKAFADRSNLRAHMQTHSAFKHYRCRQCDKSFALKS 281

  Fly   440 LLTKHSEGGC-------PGGSAGSSS 458
            .|.||.|..|       |...||.:|
Human   282 YLHKHCEAACAKAAEPPPPTPAGPAS 307

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
esgNP_476600.1 zf-C2H2 309..331 CDD:278523 9/21 (43%)
C2H2 Zn finger 311..331 CDD:275370 9/19 (47%)
zf-C2H2 344..366 CDD:278523 10/21 (48%)
C2H2 Zn finger 346..366 CDD:275368 10/19 (53%)
zf-C2H2 370..392 CDD:278523 17/21 (81%)
C2H2 Zn finger 372..392 CDD:275368 16/19 (84%)
zf-H2C2_2 385..408 CDD:290200 16/22 (73%)
zf-C2H2 398..420 CDD:278523 16/21 (76%)
C2H2 Zn finger 400..420 CDD:275368 15/19 (79%)
C2H2 Zn finger 428..444 CDD:275368 6/15 (40%)
SCRT2NP_149120.1 SNAG domain. /evidence=ECO:0000250 1..20 120/351 (34%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 34..90 18/84 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 116..148 5/33 (15%)
C2H2 Zn finger 157..177 CDD:275368 9/19 (47%)
COG5048 <210..>277 CDD:227381 48/66 (73%)
C2H2 Zn finger 214..234 CDD:275368 16/19 (84%)
zf-H2C2_2 227..250 CDD:290200 16/22 (73%)
C2H2 Zn finger 242..262 CDD:275368 15/19 (79%)
zf-H2C2_2 254..278 CDD:290200 14/23 (61%)
C2H2 Zn finger 270..286 CDD:275368 6/15 (40%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG2462
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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