DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment esg and scrt1a

DIOPT Version :9

Sequence 1:	NP_476600.1	Gene:	esg / 34903	FlyBaseID:	FBgn0001981	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	NP_001107073.1	Gene:	scrt1a / 564658	ZFINID:	ZDB-GENE-080219-30	Length:	279	Species:	Danio rerio

Alignment Length:	256	Identity:	102/256 - (39%)
Similarity:	137/256 - (53%)	Gaps:	29/256 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   231 APISPAYSENSYYSMRSMTP-----ESSCSSSLPEDLSLK---HKNLNLNLNTSQPGEQAAAKTG 287
            |.||..:.|.:|.| ..|||     ||.....:|....:.   |.:.....:......|:...:|
Zfish    29 ADISLRFHEKAYIS-DYMTPAPYDGESDSGIKVPSPGPIYDSIHSDYGAPDSDQPDSPQSEISSG 92

  Fly   288 DMSPET-------------MPNASAKKDKNQP---PRYQCPDCQKSYSTFSGLTKHQQFHCPAAE 336
            .::.:|             ....|.:|..:.|   .|:.|.:|.|:|:|.|.|::|:|.| .:.:
Zfish    93 YINGDTAVSEGYTVDAFFITDGRSRRKAISSPRTLQRHTCNECGKTYATSSNLSRHKQTH-RSLD 156

  Fly   337 GNQVKKSFSCKDCDKTYVSLGALKMHIRTHTLPCKCNLCGKAFSRPWLLQGHIRTHTGEKPFSCQ 401
            ....||   |..|.|.|||:.|:.||:.||.|..||::||||||||||||||:|:|||||||.|.
Zfish   157 SKMAKK---CPTCGKVYVSMPAMAMHLLTHDLKHKCDICGKAFSRPWLLQGHMRSHTGEKPFGCA 218

  Fly   402 HCHRAFADRSNLRAHLQTHSDIKKYSCTSCSKTFSRMSLLTKHSEGGCPGGSAGSSSSSEL 462
            ||.:|||||||||||:||||..|.|.|..|:|||:..|.|.||.|..|..|:....|..|:
Zfish   219 HCGKAFADRSNLRAHMQTHSAFKHYKCKRCNKTFALKSYLNKHYESACFKGAFAPLSPMEV 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
esg	NP_476600.1	zf-C2H2	309..331	CDD:278523	9/21 (43%)
		C2H2 Zn finger	311..331	CDD:275370	9/19 (47%)
		zf-C2H2	344..366	CDD:278523	9/21 (43%)
		C2H2 Zn finger	346..366	CDD:275368	9/19 (47%)
		zf-C2H2	370..392	CDD:278523	17/21 (81%)
		C2H2 Zn finger	372..392	CDD:275368	16/19 (84%)
		zf-H2C2_2	385..408	CDD:290200	16/22 (73%)
		zf-C2H2	398..420	CDD:278523	16/21 (76%)
		C2H2 Zn finger	400..420	CDD:275368	15/19 (79%)
		C2H2 Zn finger	428..444	CDD:275368	7/15 (47%)
scrt1a	NP_001107073.1	zf-C2H2	130..152	CDD:278523	9/21 (43%)
		C2H2 Zn finger	132..152	CDD:275368	9/19 (47%)
		C2H2 Zn finger	163..180	CDD:275371	8/16 (50%)
		COG5048	187..>263	CDD:227381	53/75 (71%)
		zf-C2H2	187..209	CDD:278523	17/21 (81%)
		C2H2 Zn finger	189..209	CDD:275368	16/19 (84%)
		C2H2 Zn finger	217..237	CDD:275368	15/19 (79%)
		zf-C2H2	217..237	CDD:278523	15/19 (79%)
		zf-H2C2_2	229..253	CDD:290200	15/23 (65%)
		C2H2 Zn finger	245..261	CDD:275368	7/15 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910