DRSC/TRiP Functional Genomics Resources

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Protein Alignment esg and Zfp410

DIOPT Version :9

Sequence 1:NP_476600.1 Gene:esg / 34903 FlyBaseID:FBgn0001981 Length:470 Species:Drosophila melanogaster
Sequence 2:NP_659082.1 Gene:Zfp410 / 52708 MGIID:1289280 Length:478 Species:Mus musculus


Alignment Length:370 Identity:98/370 - (26%)
Similarity:142/370 - (38%) Gaps:103/370 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   160 LIAPSSPSDSLGSLSPPPHHYLHGRASSVSP---PMRSEIIHRPIGVRQHRFLPYPQMPG----- 216
            ::...:|:.:..|...|....|.....:|.|   ..|::.:.     :...||..|:.|.     
Mouse    54 MLPDETPNHANSSKEVPSSAVLRSLQVNVGPDGEETRAQTVQ-----KSPEFLTTPESPSLLQDL 113

  Fly   217 YPS--------------LGGYTHTHHHHAPISPAYSENSYYSMRSMTPES--------SCSSSLP 259
            .||              ||.               |...:..::..|.:|        |..||:|
Mouse   114 QPSDSTSFILLNLTRAGLGS---------------SAEHFVFVQDETEDSGADFLSAESTDSSIP 163

  Fly   260 EDL---SLKHKN--------LNLNLNTSQPGEQAAAKTGDMSPETMPNASAKKDKNQPPRYQCPD 313
            ..|   .|.|.:        |..|..|...||.....:||..|         ||....|:.:   
Mouse   164 WFLRVQELAHDSLIAATRAQLAKNAKTGSNGENVHLGSGDGQP---------KDSGPLPQAE--- 216

  Fly   314 CQKSYSTFSGLTK------HQQFHCPAAEGNQVKKSFSC--KDCDKTYVSLGALKMHIRTHT--L 368
             :|...|..|..:      |.::|   .:.::.::||.|  :.|.|::..|..||:|:|||.  .
Mouse   217 -KKLKCTVEGCDRTFVWPAHFKYH---LKTHRNERSFICPAEGCGKSFYVLQRLKVHMRTHNGEK 277

  Fly   369 PCKCNL--CGKAFSRPWLLQGHIRTHTGEKPFSC--QHCHRAFADRSNLRAHLQTHSDIKKYSCT 429
            |..|:.  |||.|:....|:.|.|.|||||||.|  |.|.|:||:.|:||.||..||..|.:.|.
Mouse   278 PFMCHESGCGKQFTTAGNLKNHRRIHTGEKPFLCEAQGCGRSFAEYSSLRKHLVVHSGEKPHQCQ 342

  Fly   430 SCSKTF----SRMSLLTKHSEGGCPGGSAGSSSSSELNYAGYAEP 470
            .|.|||    ||...:.||.   ...|:.||....:.     |||
Mouse   343 VCGKTFSQSGSRNVHMRKHH---LQLGTTGSQEQDQT-----AEP 379

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
esgNP_476600.1 zf-C2H2 309..331 CDD:278523 4/27 (15%)
C2H2 Zn finger 311..331 CDD:275370 4/25 (16%)
zf-C2H2 344..366 CDD:278523 9/23 (39%)
C2H2 Zn finger 346..366 CDD:275368 8/21 (38%)
zf-C2H2 370..392 CDD:278523 8/23 (35%)
C2H2 Zn finger 372..392 CDD:275368 8/21 (38%)
zf-H2C2_2 385..408 CDD:290200 14/24 (58%)
zf-C2H2 398..420 CDD:278523 12/23 (52%)
C2H2 Zn finger 400..420 CDD:275368 11/21 (52%)
C2H2 Zn finger 428..444 CDD:275368 7/19 (37%)
Zfp410NP_659082.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 84..113 6/33 (18%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 187..214 9/35 (26%)
SFP1 <189..300 CDD:227516 33/126 (26%)
C2H2 Zn finger 221..243 CDD:275368 4/24 (17%)
C2H2 Zn finger 251..273 CDD:275368 8/21 (38%)
zf-H2C2_2 265..292 CDD:372612 12/26 (46%)
C2H2 Zn finger 281..303 CDD:275368 8/21 (38%)
zf-H2C2_2 295..321 CDD:372612 14/25 (56%)
C2H2 Zn finger 311..333 CDD:275368 11/21 (52%)
zf-H2C2_2 325..350 CDD:372612 12/24 (50%)
C2H2 Zn finger 341..361 CDD:275368 7/19 (37%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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