DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment esg and CG4730

DIOPT Version :9

Sequence 1:	NP_476600.1	Gene:	esg / 34903	FlyBaseID:	FBgn0001981	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	NP_001262965.1	Gene:	CG4730 / 43099	FlyBaseID:	FBgn0039355	Length:	392	Species:	Drosophila melanogaster

Alignment Length:	191	Identity:	53/191 - (27%)
Similarity:	81/191 - (42%)	Gaps:	28/191 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   274 NTSQPGE-QAAAKTGDMSPETMPNASAKKDKNQPP---------------RYQCPDCQKSYSTFS 322
            ||.|..: :......||:.|.:  ....::|.:.|               :..|..|.|.:...|
  Fly   132 NTEQEDDVEDEENEADMNEEFL--MEEIEEKQETPIDSLEDIVPRNRHTGKSNCKFCHKEFRNHS 194

  Fly   323 GLTKHQQFHCPAAEGNQVKKSFSCKDCDKTYVSLGALKMHI--RTHTLPCKCNLCGKAFSRPWLL 385
            .:.|||..|...      :.:|.|..||:.|::..|||:|:  :.......|:.|||.|:....|
  Fly   195 RMAKHQMIHLAN------RPNFRCSQCDRVYLTKQALKVHVDSKHRQSGVHCDTCGKVFAIAKAL 253

  Fly   386 QGHIRTHTGEKPFSCQHCHRAFADRSNLRAHLQTHSDIKKYSC--TSCSKTFSRMSLLTKH 444
            :.|.|.|..:.|:||..|.|.||.||:|..|.|......::.|  ..|.|:|:..|.|..|
  Fly   254 EIHKRYHNRDFPYSCDLCDRRFAQRSHLTVHQQVKHSGSRFICEFPGCQKSFTSSSSLRNH 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
esg	NP_476600.1	zf-C2H2	309..331	CDD:278523	7/21 (33%)
		C2H2 Zn finger	311..331	CDD:275370	7/19 (37%)
		zf-C2H2	344..366	CDD:278523	9/23 (39%)
		C2H2 Zn finger	346..366	CDD:275368	8/21 (38%)
		zf-C2H2	370..392	CDD:278523	8/21 (38%)
		C2H2 Zn finger	372..392	CDD:275368	8/19 (42%)
		zf-H2C2_2	385..408	CDD:290200	9/22 (41%)
		zf-C2H2	398..420	CDD:278523	11/21 (52%)
		C2H2 Zn finger	400..420	CDD:275368	10/19 (53%)
		C2H2 Zn finger	428..444	CDD:275368	6/17 (35%)
CG4730	NP_001262965.1	zf-AD	46..124	CDD:285071
		C2H2 Zn finger	183..203	CDD:275368	7/19 (37%)
		C2H2 Zn finger	212..232	CDD:275368	8/19 (42%)
		C2H2 Zn finger	240..260	CDD:275368	8/19 (42%)
		C2H2 Zn finger	268..289	CDD:275368	10/20 (50%)
		C2H2 Zn finger	296..318	CDD:275368	7/19 (37%)
		C2H2 Zn finger	325..346	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468413
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930