Protein Alignment esg and CG8301

DIOPT Version :10

• Sequence 1: NP_476600.1
• Gene: esg / 34903
• FlyBaseID: FBgn0287768
• Length: 470
• Species: Drosophila melanogaster
• Sequence 2: NP_649915.1
• Gene: CG8301 / 41160
• FlyBaseID: FBgn0037717
• Length: 607
• Species: Drosophila melanogaster
• Alignment Length: 554
• Identity: 102/554 - (18%)
• Similarity: 171/554 - (30%)
• Gaps: 189/554 - (34%)

  Fly     5 EDMLVEKNYSKCPLKKRPVNYQFEAPQNHSNTPNEPQDLCVKKMEILEENPSEELINVSDCCEDE 69
            ||:...:.:.:....|.......|...|  ||.::|.::.|                       :
  Fly   107 EDLEPAEEHQETETTKPTTTVSAETQPN--NTASDPIEIFV-----------------------D 146

  Fly    70 GVDVDHTDDEHIEEE-----DEDVD---VDVDSDPNQTQAAALAAAAAVAAAAAASVVVPTPTYP 126
            .||:|..::|..|||     ||:|:   .|..:.|..|.:.|.
  Fly   147 AVDIDEAEEEEEEEEQQQQYDEEVEEPITDESAPPQLTISYAC---------------------- 189

  Fly   127 KY---PWNNFHMSPYTAEFYRTINQQGHQILPLRGDLIAPSSPSDSLGSLSPPPHHYLHGRASSV 188
            |:   |..|:.:.....|.   || ..|       |...|.:..:............:|.::|.|
  Fly   190 KFCLRPQENYQLQQLLLEH---IN-ASH-------DPEQPYNCPECEARFQDAASRTVHLKSSHV 243

  Fly   189 SPPMRSEIIHRPIGVRQHRFLPYPQMPGYPSLGGYTHTHHHHAPISPAYSENSYYSMRSM----- 248
            .......:..:..|.|.             :|..:...:|.......|..|..:|:.:|:
  Fly   244 EKQHACGVCGKKYGDRH-------------NLRHHVEKYHSETDFECALCEKRFYTRKSLNYHMK 295

  Fly   249 --TPES--SCSSSLPEDLSLKHKNLN------------------------LNLNT------SQPG 279
              .|:.  .|..|..|.|.:..::|.                        ::|.|      .|.|
  Fly   296 WHNPDRQFKCRHSGCERLFISQRHLMCHEATHSGTSSRKSEHCGFCGKTFIHLKTLRWHIYRQHG 360

  Fly   280 EQAAAKTGD-----------------------------------------------MSPETMPNA 297
            .:...|..:                                               ||.|.:...
  Fly   361 GEKPYKCANCTEVFASYAEKRIHMLERHRENLTAIERSECMLCRQPFSSEPDLIHHMSAEHLQRP 425

  Fly   298 SA------------KKDKNQPPRYQCPDCQKSYSTFSGLTKHQQFHCPAAEGNQVKKSFSCKDCD 350
            .|            |:::.....:||..|.:.::..|.|.:|...|      ::..:..:|..|.
  Fly   426 GAPIIANNKRVLQQKRERQYSGLFQCGSCSQRFNMKSALERHAAVH------SEKDRPHACPHCS 484

  Fly   351 KTYVSLGALKMHIRTH--TLPCKCNLCGKAFSRPWLLQGHIRTH-TGEKPFSCQHCHRAFADRSN 412
            |.:.....:|.||:||  ..|..|::|||||:..::|..|..:| ..||.|.|..|.||:....:
  Fly   485 KRFKRAQDMKWHIKTHEKEKPNVCDVCGKAFALKYVLTQHRLSHEVLEKNFKCNVCGRAYLFEKS 549

  Fly   413 LRAHLQTHSDIKKYSCTSCSKTFSRMSLLTKHSE 446
            ||.|.:||:....|.|..|.:.|.....|..|.:
  Fly   550 LRLHQRTHTGKTYYKCDLCQERFVTHIKLKTHMQ 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
esg	NP_476600.1	KREPA	<278..>329	CDD:483960	13/109 (12%)
		zf-C2H2	309..331	CDD:395048	6/21 (29%)
		C2H2 Zn finger	311..331	CDD:275370	5/19 (26%)
		zf-C2H2	344..366	CDD:395048	6/21 (29%)
		C2H2 Zn finger	346..366	CDD:275368	6/19 (32%)
		zf-C2H2	370..392	CDD:395048	8/21 (38%)
		C2H2 Zn finger	372..392	CDD:275368	8/19 (42%)
		zf-H2C2_2	385..408	CDD:463886	10/23 (43%)
		zf-C2H2	398..420	CDD:395048	8/21 (38%)
		C2H2 Zn finger	400..420	CDD:275368	7/19 (37%)
		C2H2 Zn finger	428..444	CDD:275368	4/15 (27%)
CG8301	NP_649915.1	zf-AD	3..88	CDD:462262
		COG5048	198..>508	CDD:227381	50/339 (15%)
		C2H2 Zn finger	221..241	CDD:275368	1/19 (5%)
		C2H2 Zn finger	249..269	CDD:275368	3/32 (9%)
		C2H2 Zn finger	277..297	CDD:275368	4/19 (21%)
		C2H2 Zn finger	305..327	CDD:275368	5/21 (24%)
		C2H2 Zn finger	338..359	CDD:275368	2/20 (10%)
		C2H2 Zn finger	367..384	CDD:275368	0/16 (0%)
		C2H2 Zn finger	400..420	CDD:275368	2/19 (11%)
		C2H2 Zn finger	451..471	CDD:275368	5/19 (26%)
		C2H2 Zn finger	480..500	CDD:275368	6/19 (32%)
		C2H2 Zn finger	508..528	CDD:275368	8/19 (42%)
		SUF4-like	536..>586	CDD:411020	15/48 (31%)
		C2H2 Zn finger	537..558	CDD:411020	8/20 (40%)
		C2H2 Zn finger	537..557	CDD:275368	7/19 (37%)
		C2H2 Zn finger	565..586	CDD:411020	5/19 (26%)
		C2H2 Zn finger	565..582	CDD:275368	4/16 (25%)