DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment esg and Scrt2

DIOPT Version :9

Sequence 1:	NP_476600.1	Gene:	esg / 34903	FlyBaseID:	FBgn0001981	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	NP_001178834.1	Gene:	Scrt2 / 366229	RGDID:	1564796	Length:	305	Species:	Rattus norvegicus

Alignment Length:	344	Identity:	120/344 - (34%)
Similarity:	156/344 - (45%)	Gaps:	63/344 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   120 VPTPTYPKYPWNNFHMSPYTAEFYRTINQQGHQILPLRGDLIAPSSPSDSLGSLSPPPHHYLHGR 184
            ||.|||                         |   ||....:.|       |:..||..   :|.
  Rat    20 VPAPTY-------------------------H---PLETAYVLP-------GTRGPPGD---NGY 46

  Fly   185 ASSVSPPMRSEIIHRPIGVRQHRFLPYPQMPGYPSLGGYTHTHHHHAPISPAYSENSYYSMRSMT 249
            .:...||...:...:| |:..     .|..|.||:..    :..:..|.||    .|..|.|...
  Rat    47 VAHCMPPSGYDGEQKP-GLEL-----APTEPAYPAAA----SEEYSDPESP----QSSLSARYFR 97

  Fly   250 PESSCSSSLPEDLSLKHKNLNLNLNTSQPGEQAAAKTGDMSPETMPNASAKKDKNQPPRYQCPDC 314
            .|::.:.|...|........:........|:.|.|..|....|....:.|......  |:.|.:|
  Rat    98 GEAAVTDSYSMDAFFISDGRSRRRRAGAGGDAAGAGDGGGGGERAGRSGATAGGGH--RHACAEC 160

  Fly   315 QKSYSTFSGLTKHQQFHCPAAEGNQVKKSFSCKDCDKTYVSLGALKMHIRTHTLPCKCNLCGKAF 379
            .|:|:|.|.|::|:|.| .:.:....:|   |..|.|.|||:.||.||:.||.|..||.:|||||
  Rat   161 GKTYATSSNLSRHKQTH-RSLDSQLARK---CPTCGKAYVSMPALAMHVLTHNLRHKCGVCGKAF 221

  Fly   380 SRPWLLQGHIRTHTGEKPFSCQHCHRAFADRSNLRAHLQTHSDIKKYSCTSCSKTFSRMSLLTKH 444
            |||||||||:|:|||||||.|.||.:|||||||||||:||||..|.|.|..|.|:|:..|.|.||
  Rat   222 SRPWLLQGHMRSHTGEKPFGCAHCGKAFADRSNLRAHMQTHSAFKHYRCRQCDKSFALKSYLHKH 286

  Fly   445 SEGGC-----PGGSAGSSS 458
            .|..|     |..|||.:|
  Rat   287 CEAACVKAAEPPPSAGPAS 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
esg	NP_476600.1	zf-C2H2	309..331	CDD:278523	9/21 (43%)
		C2H2 Zn finger	311..331	CDD:275370	9/19 (47%)
		zf-C2H2	344..366	CDD:278523	10/21 (48%)
		C2H2 Zn finger	346..366	CDD:275368	10/19 (53%)
		zf-C2H2	370..392	CDD:278523	17/21 (81%)
		C2H2 Zn finger	372..392	CDD:275368	16/19 (84%)
		zf-H2C2_2	385..408	CDD:290200	16/22 (73%)
		zf-C2H2	398..420	CDD:278523	16/21 (76%)
		C2H2 Zn finger	400..420	CDD:275368	15/19 (79%)
		C2H2 Zn finger	428..444	CDD:275368	6/15 (40%)
Scrt2	NP_001178834.1	C2H2 Zn finger	157..177	CDD:275368	9/19 (47%)
		COG5048	<210..>277	CDD:227381	48/66 (73%)
		zf-C2H2	212..234	CDD:278523	17/21 (81%)
		C2H2 Zn finger	214..234	CDD:275368	16/19 (84%)
		zf-H2C2_2	227..250	CDD:290200	16/22 (73%)
		C2H2 Zn finger	242..262	CDD:275368	15/19 (79%)
		zf-C2H2	242..262	CDD:278523	15/19 (79%)
		zf-H2C2_2	254..278	CDD:290200	14/23 (61%)
		C2H2 Zn finger	270..286	CDD:275368	6/15 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2462
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	179	1.000	Inparanoid score	I3910
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.860