DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment esg and snai-1

DIOPT Version :9

Sequence 1:	NP_476600.1	Gene:	esg / 34903	FlyBaseID:	FBgn0001981	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	NP_499902.2	Gene:	snai-1 / 186874	WormBaseID:	WBGene00019299	Length:	193	Species:	Caenorhabditis elegans

Alignment Length:	178	Identity:	91/178 - (51%)
Similarity:	118/178 - (66%)	Gaps:	14/178 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   289 MSPETMPNASAKKDK-----NQPPRYQCPDCQKSYSTFSGLTKHQQFHCPAAEGNQVKKSFSCKD 348
            :||:..|::|:....     ||  :..|..|:|:|.|:.||.:|.|||   .||   |...||..
Worm    18 ISPDPAPSSSSSSASCSSLDNQ--KLVCQFCKKTYLTYFGLRRHLQFH---KEG---KLQQSCPH 74

  Fly   349 CDKTYVSLGALKMHIRTHTLPCKCNLCGKAFSRPWLLQGHIRTHTGEKPFSCQHCHRAFADRSNL 413
            |.|.|.|.||||||::||:|||.||.|||:|||||||:||:|||||||||.|:.|.|.|||||||
Worm    75 CKKVYRSPGALKMHLKTHSLPCVCNDCGKSFSRPWLLKGHLRTHTGEKPFGCEFCGRCFADRSNL 139

  Fly   414 RAHLQTHSDIKKYSCTSCSKTFSRMSLLTKHSEGGCPGGSAGSSSSSE 461
            ||||||||..||:.|:.|.::|:|:.:..:| |..|.||.:|..:..|
Worm   140 RAHLQTHSGEKKHRCSRCGQSFARVQVRQRH-EQCCRGGGSGGEAEKE 186

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
esg	NP_476600.1	zf-C2H2	309..331	CDD:278523	9/21 (43%)
		C2H2 Zn finger	311..331	CDD:275370	9/19 (47%)
		zf-C2H2	344..366	CDD:278523	12/21 (57%)
		C2H2 Zn finger	346..366	CDD:275368	11/19 (58%)
		zf-C2H2	370..392	CDD:278523	16/21 (76%)
		C2H2 Zn finger	372..392	CDD:275368	15/19 (79%)
		zf-H2C2_2	385..408	CDD:290200	15/22 (68%)
		zf-C2H2	398..420	CDD:278523	16/21 (76%)
		C2H2 Zn finger	400..420	CDD:275368	15/19 (79%)
		C2H2 Zn finger	428..444	CDD:275368	4/15 (27%)
snai-1	NP_499902.2	C2H2 Zn finger	72..92	CDD:275368	11/19 (58%)
		COG5048	98..>155	CDD:227381	43/56 (77%)
		C2H2 Zn finger	98..118	CDD:275368	15/19 (79%)
		C2H2 Zn finger	126..146	CDD:275368	15/19 (79%)
		zf-H2C2_2	138..163	CDD:290200	15/24 (63%)
		C2H2 Zn finger	154..170	CDD:275368	4/15 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I8191
eggNOG	1	0.900	-	-		E1_KOG2462
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1955
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004977
OrthoInspector	1	1.000	-	-		otm14747
orthoMCL	1	0.900	-	-		OOG6_107394
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3546
SonicParanoid	1	1.000	-	-		X955
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.650