DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment esg and ztf-23

DIOPT Version :9

Sequence 1:	NP_476600.1	Gene:	esg / 34903	FlyBaseID:	FBgn0001981	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	NP_491096.1	Gene:	ztf-23 / 171880	WormBaseID:	WBGene00021846	Length:	419	Species:	Caenorhabditis elegans

Alignment Length:	215	Identity:	59/215 - (27%)
Similarity:	91/215 - (42%)	Gaps:	41/215 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   236 AYSENSYYSMRSMTPESSCSSSLPEDLSLKHKNLNLNLNTSQPGEQAAAKTGDMSPETMPNASAK 300
            |:.::.|.....::|:....||         .|.:|....::       :...:....:.||:.:
Worm   173 AHDDSDYILEDDLSPQGPIRSS---------NNYHLKYIRTR-------RMDKLIDNVVVNATQR 221

  Fly   301 KDKNQPPRYQCPDCQKSYSTFSGLTKHQQFHCPAAEG--NQVKKS-FSCKDCDKTYVSLGALKMH 362
            ....|      .||..|...|             |:|  |..|.. |||..|.:|:.....|..|
Worm   222 DSPEQ------EDCSTSGVAF-------------ADGQTNSGKMGRFSCDRCSRTFKYQSKLDEH 267

  Fly   363 IRTH--TLPCKCNLCGKAFSRPWLLQGHIRTHTGEKPFSCQ-HCHRAFADRSNLRAHLQTHSDIK 424
            .|||  ..|.:|:.|.:.||:...|:.|:|.||||:||.|| .|.:.||..|....|.:|||..:
Worm   268 RRTHLGVKPFQCHYCTRQFSQRGALKTHMRLHTGERPFVCQWECGKQFASSSAKSHHEKTHSGER 332

  Fly   425 KYSCTSCSKTFSRMSLLTKH 444
            .|.|..|.|:|::.|.:.:|
Worm   333 PYICNVCGKSFTKNSHVIRH 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
esg	NP_476600.1	zf-C2H2	309..331	CDD:278523	4/21 (19%)
		C2H2 Zn finger	311..331	CDD:275370	4/19 (21%)
		zf-C2H2	344..366	CDD:278523	8/21 (38%)
		C2H2 Zn finger	346..366	CDD:275368	6/19 (32%)
		zf-C2H2	370..392	CDD:278523	7/21 (33%)
		C2H2 Zn finger	372..392	CDD:275368	7/19 (37%)
		zf-H2C2_2	385..408	CDD:290200	12/23 (52%)
		zf-C2H2	398..420	CDD:278523	8/22 (36%)
		C2H2 Zn finger	400..420	CDD:275368	7/20 (35%)
		C2H2 Zn finger	428..444	CDD:275368	5/15 (33%)
ztf-23	NP_491096.1	C2H2 Zn finger	251..271	CDD:275368	6/19 (32%)
		zf-H2C2_2	264..288	CDD:290200	9/23 (39%)
		C2H2 Zn finger	279..299	CDD:275368	7/19 (37%)
		zf-H2C2_2	291..317	CDD:290200	13/25 (52%)
		C2H2 Zn finger	307..328	CDD:275368	7/20 (35%)
		zf-H2C2_2	324..344	CDD:290200	8/19 (42%)
		C2H2 Zn finger	336..357	CDD:275368	6/17 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000