DRSC/TRiP Functional Genomics Resources

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Protein Alignment nht and Taf4b

DIOPT Version :9

Sequence 1:NP_523574.4 Gene:nht / 34902 FlyBaseID:FBgn0041103 Length:245 Species:Drosophila melanogaster
Sequence 2:NP_001093919.1 Gene:Taf4b / 72504 MGIID:2152345 Length:855 Species:Mus musculus


Alignment Length:260 Identity:56/260 - (21%)
Similarity:106/260 - (40%) Gaps:51/260 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    20 INDLILPDSGSQDASKAKV----------SIKKNQRASFFDRSSIYKKIM----KHLSQGNQADD 70
            |||:......:.|...|.:          .|:..:...|....::.|:|:    ||......:|.
Mouse   610 INDVTFMAEVNLDEENACILAAHSDFVGTLIQSCKEEPFLVIGALQKRILDIGKKHDITELNSDA 674

  Fly    71 INISEQEWLLDSFLAALETYMKHVVKKTIELCEHRTSYHLHNDERCVMKNDMRVTMMFL------ 129
            :|:...         |.:..::.:::|...:.:||.:.: ...|..::..|.|..:.||      
Mouse   675 VNLISH---------ATQERLRGLLEKLTTIAQHRMTIY-KGSENYILSTDTRSQLKFLEKLDQL 729

  Fly   130 ----NDLEIADY--------GSSDDETGFYRKRRAENIDEERKVARLE--SVNDTALLAISGRKR 180
                .|||..:.        .:.:|......|::|:.: ::.::|:::  ..|.|||.||..||:
Mouse   730 EKQRKDLEEREMLLKAAKSRSNKEDPEQLRLKQKAKEL-QQLELAQIQYRDANLTALAAIGPRKK 793

  Fly   181 PGEQLAPES---APSGSKVAKLTGAPIQRACAPRFKHMNIRDVLQFMEEDRRYARSNMLFEAYLK 242
            ...:...||   .||.|..:.||..   :...||...:.:||::..||::|....|..|:.|.||
Mouse   794 RPLESGNESFKDNPSTSGTSSLTAT---KPFRPRITRICLRDLIFCMEQEREMKYSRALYLALLK 855

  Fly   243  242
            Mouse   856  855

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
nhtNP_523574.4 TAF4 10..238 CDD:173965 53/254 (21%)
Taf4bNP_001093919.1 Sufficient for interaction with ZNF628. /evidence=ECO:0000269|PubMed:31932482 99..240
TAFH 257..343 CDD:284862
Required for interaction with P65/RELA. /evidence=ECO:0000250|UniProtKB:Q92750 504..526
Nuclear export signal. /evidence=ECO:0000250|UniProtKB:Q92750 509..549
TAF4 610..850 CDD:283017 52/253 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 793..817 6/23 (26%)
Required for interaction with TAF12. /evidence=ECO:0000250|UniProtKB:Q92750 823..855 10/31 (32%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG2341
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0001841
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR15138
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
43.910

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