DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cul3 and AT1G59800

DIOPT Version :9

Sequence 1:	NP_723909.2	Gene:	Cul3 / 34896	FlyBaseID:	FBgn0261268	Length:	934	Species:	Drosophila melanogaster
Sequence 2:	NP_176189.1	Gene:	AT1G59800 / 842273	AraportID:	AT1G59800	Length:	255	Species:	Arabidopsis thaliana

Alignment Length:	240	Identity:	59/240 - (24%)
Similarity:	118/240 - (49%)	Gaps:	9/240 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   190 ETIWASLKNAIQEIQK--KNNSGLSFEQ-----LYRNAYNMVLHKHGNRLYYGLREVVSEHLEHK 247
            |..|::::....::.:  :..|..:|.|     ::...|.:..:|:..:||...||::..:....
plant    10 EVEWSNIQQGFTKLIRMIEGESEPAFNQEIMMMMHTATYRICAYKNPQQLYDKYRELIENYAIQT 74

  Fly   248 VRADVLEALHSNFLPKLNQAWTDHQTSMVMIRDILMYMDRVYVQQREVDNVYNLGLILFRDQVVR 312
            |...:.|......|.:|.:.|..|:..:.:....|:|:|..::.::.:.::..:||..|||||
plant    75 VLPSLREKHDECMLRELAKRWNAHKLLVRLFSRRLVYLDDSFLSKKGLPSLREVGLNCFRDQV-- 137

  Fly   313 YSEIQKALREKLLGMVMEERHGEAINHLAIKNACSMLITLGINSRTVYEEDFEKPFLAQSAAFYK 377
            |.|:|....|.:|.::.:||.||.|:...::|...:.:..|:.:...||||||:..|..:|::|.
plant   138 YREMQSMAAEAILALIHKEREGEQIDRELVRNVIDVFVENGMGTLKKYEEDFERLMLQDTASYYS 202

  Fly   378 FESQNFLAENNAGVYIKKVEARITEESSRAALYLDKDTEPRIVRV 422
            .::..::.|.:...|..|.:..:..|..|...||...|||::..|
plant   203 SKASRWIQEESCLDYTLKPQQCLQRERERVTHYLHPTTEPKLFEV 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cul3	NP_723909.2	Cullin	196..831	CDD:279260	57/234 (24%)
		CULLIN	582..724	CDD:214545
		Cullin_Nedd8	866..926	CDD:287520
AT1G59800	NP_176189.1	Cullin	41..>255	CDD:279260	54/209 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5647
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1040292at2759
OrthoFinder	1	1.000	-	-		FOG0000491
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820