DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cul3 and AT3G46910

DIOPT Version :9

Sequence 1:	NP_723909.2	Gene:	Cul3 / 34896	FlyBaseID:	FBgn0261268	Length:	934	Species:	Drosophila melanogaster
Sequence 2:	NP_190275.1	Gene:	AT3G46910 / 823844	AraportID:	AT3G46910	Length:	247	Species:	Arabidopsis thaliana

Alignment Length:	233	Identity:	50/233 - (21%)
Similarity:	101/233 - (43%)	Gaps:	36/233 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   188 YVETIWASLKNAIQEIQKKNNSGLSFEQLYRNAYN--MVLHKHGNRLYYGLREVVSEHLEHKVRA 250
            |||..|..||.||:.|........:...|: ||.|  ......|..||    :::.|..|..:.|
plant    25 YVEDAWTMLKPAIRAIFLDEPQDFACSGLF-NAVNKSWCEKSSGEALY----KLILEECEIYISA 84

  Fly   251 DVLEALHSN-------FLPKLNQAWTDHQTSMVMIRDILMYMDRVYVQQREV---DNVYNLGLIL 305
             .:::|.|.       ||..|.:.|.|       .|..|.::..:...:.:.   .:|::||..|
plant    85 -AIQSLESQCDTDPSLFLSLLEKCWLD-------FRRKLQFLCSIAGGEGQTVGPHSVWDLGSEL 141

  Fly   306 FRDQVVRYSEIQKALREKLLGMVMEERHGEAINHLAIKNACSMLITLGIN----------SRTVY 360
            ....:....:::..|...:|.::.::|...:::...:||....::::.:.          .:::|
plant   142 SPKHLFSAQKVRDKLLSIILQLIRDQRSFMSVDMTQLKNTTRPVMSVHMTQLNNLRGLFYGQSLY 206

  Fly   361 EED-FEKPFLAQSAAFYKFESQNFLAENNAGVYIKKVE 397
            :.. |:|||:..:..||..|:..|..:::..:|:|:||
plant   207 KSPFFKKPFIDCAVEFYSAEAMQFKEQSDIPLYLKRVE 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cul3	NP_723909.2	Cullin	196..831	CDD:279260	46/225 (20%)
		CULLIN	582..724	CDD:214545
		Cullin_Nedd8	866..926	CDD:287520
AT3G46910	NP_190275.1	Cullin	33..>244	CDD:279260	44/223 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5647
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1040292at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820