DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pol32 and Pold3

DIOPT Version :9

Sequence 1:	NP_001188816.1	Gene:	Pol32 / 34892	FlyBaseID:	FBgn0283467	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	NP_001019921.1	Gene:	Pold3 / 293144	RGDID:	1312027	Length:	462	Species:	Rattus norvegicus

Alignment Length:	500	Identity:	113/500 - (22%)
Similarity:	192/500 - (38%)	Gaps:	122/500 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LDDCMIDFDRCVLVTDLLEEYK-LSY------KEVNDVLEAYI---KEQEPATKFEKRFLVHGKR 61
            :|:.:.|.::.|       .|| |||      .:...:|..|:   :::....:....:||.|..
  Rat    10 IDEFVTDQNKIV-------TYKWLSYTLGVHVNQAKQMLYEYVERKRKENSGAQLHVTYLVSGSL 67

  Fly    62 KTQGSDSGEDLYSVVLESRMQDWLAKVQ-DAESQLYSVKIAGGTKAPAAIFKPMQHLEVKLAKVE 125
            ...|....:  .:||.|.|::...:|:. .|...:||::     ||......|:.:.:..:.|
  Rat    68 IQNGHSCHK--VAVVREDRLEAVKSKLAVTASIHVYSIQ-----KAMLKDSGPLFNTDYDILK-- 123

  Fly   126 QRPGAGKIVPSANGTTPHNGVK---SEPTKSEPSKSAVKLEPSKSSLKSEPAKSK----AEKPVA 183
                     .:....:..:.::   :.|.....|.|:.|.|.|.....||...|:    ...|.|
  Rat   124 ---------SNLQNCSKFSAIQCAAAVPRAPAESSSSRKFEQSNLQAASETQASELTTNGHGPPA 179

  Fly   184 SKSSPE----------------------DKKTSPKE--QASKAKPAAAKKGSI--NSFFTAAASK 222
            ||.:.:                      |.||..:|  .||.|...|..||::  |.|..||.||
  Rat   180 SKQASQQPKGIMGMLISKAATKTQDTNKDTKTEAREVTSASSAGGKAPGKGNVMSNFFGKAAMSK 244

  Fly   223 PK-DVKATPSKSTSGTVDNFFKKQPAGAKKSPPESEDKSKKDASNSNKKEASKKKSP--SPTKKP 284
            .| ::.:..:.....||:            .||.|..:.|..|..:.|| :|:|..|  ...|:.
  Rat   245 LKVNLDSEQAVKEEKTVE------------QPPVSVAEPKLAAPPALKK-SSRKSEPVKMQQKEK 296

  Fly   285 TTANTSMQLFDEESAESSDEEEKLDMLRRKVIESDNDSDQEKASSSKR-RRISDSEDEEQPP--- 345
            ......:.|.|||:.|:.:.::|  ..|.|:.:||:..|:..|.|.:. ..:|.|.....||
  Rat   297 KCRGKRVDLSDEEAKETENLKKK--RRRIKLPQSDSSEDEVFADSPEMFEAVSPSPPPASPPPDP 359

  Fly   346 ---------KKSADEETIALDEKMDTEPANETYLDEDGFVITQR-----------KPTKAQPANK 390
                     |:|:.|.    ..|......::|::||:|.::|::           :.||.:.|:.
  Rat   360 VPKTEPPPVKRSSGEN----KRKRKRVLKSKTFVDEEGCMVTEKVYESESCTDSEEETKMKMASA 420

  Fly   391 KVSPKAAA---PVNKKKSPPSAAKA-GKDAPKTKQAGIMNFFSKK 431
            :..|.|..   |..::|.|...|.| ||   ..:|..|..||.||
  Rat   421 QRPPAATVKREPREERKGPKKGAAALGK---ANRQVSITGFFQKK 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pol32	NP_001188816.1	CDC27	<153..431	CDD:370537	84/338 (25%)
Pold3	NP_001019921.1	CDC27	19..462	CDD:286580	109/489 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28HEU
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900