DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dao and smyd1a

DIOPT Version :9

Sequence 1:	NP_001260462.1	Gene:	dao / 34891	FlyBaseID:	FBgn0028862	Length:	882	Species:	Drosophila melanogaster
Sequence 2:	NP_991103.2	Gene:	smyd1a / 321245	ZFINID:	ZDB-GENE-030131-9825	Length:	485	Species:	Danio rerio

Alignment Length:	350	Identity:	65/350 - (18%)
Similarity:	110/350 - (31%)	Gaps:	109/350 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   326 LHTTRAVAKNALIF--ESEAVAMVPSGNCRVCDYCGITQFIPFPCIYCSNRLVVYCSRQCRFKHA 388
            |..||.::...::|  .|.|..::.|.:.:||..|...|..|..|..|  :...||.|.|:....
Zfish    21 LRGTRDLSAGEVVFAEASFAAVVLDSLSLQVCHSCFRRQVNPHRCAQC--KFAHYCDRTCQRAAW 83

  Fly   389 AIHAVECFGHQIELFESFGEVFGMPRLLQLAFRMLITGLPELLGHCRKKPTLSKLWSAI-NGGLQ 452
            ..|..||                                                 ||| |.|..
Zfish    84 DEHRKEC-------------------------------------------------SAIRNIGKA 99

  Fly   453 ERQDIAYSAVLRLERLKEERPTDTVIALALAAHILSIYLSKCTTFFDQLEKSLPTASRMSSAE-- 515
            ..:::...|.: |.|:::              |...:..|:.|| .|.||..|   |||:..:
Zfish   100 PNENVRLVARI-LWRIQK--------------HTGLVSDSQLTT-LDMLEDHL---SRMTPEDLK 145

  Fly   516 ------------WELLCAALLMRHIGQLRHRSLTACRSFVLPADPHVFSPLNEFQLWAAPMRLQE 568
                        |.....|:...::..|  ..:.:|..|.|                :....||.
Zfish   146 ELKVDVKTFYTYWPKKSKAVGEDYVSHL--FGVISCNGFTL----------------SDQRGLQS 192

  Fly   569 GHLHLLAGEVAVVSYSVYPDTLNLCRHSCSSTICAKF-SGRTVTALALLDLPAGSGIYNCFAGGN 632
            ..:.|.. .:.:|::..:|:...:..|...|.:.|.| |.|.:...||..:.||..:...:.  :
Zfish   193 VGIGLFP-NLCLVNHDCWPNCTVILNHGDQSALDASFHSSRRIELRALEPISAGQELTVSYV--D 254

  Fly   633 FQQLPREERTKQLLESGIRCHCNAC 657
            |..:..:.:.....:....|.|..|
Zfish   255 FLSVSTDRQRLLQQQYYFDCKCEHC 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dao	NP_001260462.1	TPR_11	165..235	CDD:290150
		TPR repeat	200..235	CDD:276809
		TPR repeat	243..270	CDD:276809
		zf-MYND	355..395	CDD:280009	11/39 (28%)
smyd1a	NP_991103.2	zf-MYND	52..90	CDD:280009	11/39 (28%)
smyd1a	NP_991103.2	SET	<203..252	CDD:279228	12/48 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582772
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2084
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740