back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dao and Smyd2

DIOPT Version :9

Sequence 1:	NP_001260462.1	Gene:	dao / 34891	FlyBaseID:	FBgn0028862	Length:	882	Species:	Drosophila melanogaster
Sequence 2:	NP_081072.1	Gene:	Smyd2 / 226830	MGIID:	1915889	Length:	433	Species:	Mus musculus

Alignment Length:	548	Identity:	95/548 - (17%)
Similarity:	176/548 - (32%)	Gaps:	203/548 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   337 LIFESEAVAMVPSGNCR--VCDYC-----GITQFIPFPCIYCSNRLVVYCSRQCRFKHAAIHAVE 394
            |:|...|.|.|.:...|  .|:.|     |:::     |..|  :...||..:|:.:...:|.:|
Mouse    32 LLFSCPAYACVLTVGERGHHCECCFARKEGLSK-----CGRC--KQAFYCDVECQKEDWPLHKLE 89

  Fly   395 CFGHQIELFESFGEVFGMPRLLQLAFRMLI--------TGLPELLGHCRKKPTLSKLWSAINGGL 451
            |....:     .||.:.....::|..|:|.        |...:||.....:..|.||.:
Mouse    90 CSSMVV-----LGENWNPSETVRLTARILAKQKIHPERTPSEKLLAVREFESHLDKLDN------ 143

  Fly   452 QERQDIAYSAVLRLERLKEERPTDTVIALALAAHILSIYLSKCTTFFDQLEKSLPTASRMSSAEW 516
             |::|:..|.:..|.:                      :.||...|.|
Mouse   144 -EKKDLIQSDIAALHQ----------------------FYSKYLEFPD----------------- 168

  Fly   517 ELLCAALLMRHIGQLRHRSLTA------CRSFVLPADPHVFSPLNEFQLWAAPMRLQEGHLHLLA 575
                            |.||..      |..|.:..:
Mouse   169 ----------------HSSLVVLFAQVNCNGFTIEDE---------------------------- 189

  Fly   576 GEVAVVSYSVYPDTLNLCRHSCSSTICAKFSGRTVTALALLDLPAGSGIYNCFAGGNFQQLPREE 640
             |::.:..:::|| :.|..|||...:...:.|......|:.::..|..::..:....:   |.|:
Mouse   190 -ELSHLGSAIFPD-VALMNHSCCPNVIVTYKGTLAEVRAVQEIHPGDEVFTSYIDLLY---PTED 249

  Fly   641 RTKQLLES-GIRCHCNACQLTHSDDQFHKFHRYRCDNPNCMEIFTPNALPHAPSLRWWLSEEYTQ 704
            |..:|.:| ...|.|..|  |..|....|....:..:|           |.|.::|
Mouse   250 RNDRLRDSYFFTCECREC--TTKDKDKAKVEVRKLSSP-----------PQAEAIR--------- 292

  Fly   705 PEFNGADLIMCPH--CGEYQKLEWFWAFTTSLIDCELIEERCKLYAAIERAENQLMDLHECKVAL 767
                  |::....  ..|:::.:.:.:.:..|..|||.:|  |:.:..|  ::.:..||....|:
Mouse   293 ------DMVRYARNVIEEFRRAKHYKSPSELLEICELSQE--KMSSVFE--DSNVYMLHMMYQAM 347

  Fly   768 ARLLLEQCLMVHREGATVLDDWEFNKLGSILRSVLPSVMAQYGGQSIE-YVKYFSYF-------W 824
            .     .||        .:.|||    |::          :||.:.|: |.|::..:       |
Mouse   348 G-----VCL--------YMQDWE----GAL----------KYGQKIIKPYSKHYPVYSLNVASMW 385

  Fly   825 -----DVMALSNYKCNDRELMQMLNALE 847
                 ..|.|.|....::.|.:.:..:|
Mouse   386 LKLGRLYMGLENKAAGEKALKKAIAIME 413

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.