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Protein Alignment dao and SMYD1

DIOPT Version :9

Sequence 1:	NP_001260462.1	Gene:	dao / 34891	FlyBaseID:	FBgn0028862	Length:	882	Species:	Drosophila melanogaster
Sequence 2:	NP_938015.1	Gene:	SMYD1 / 150572	HGNCID:	20986	Length:	490	Species:	Homo sapiens

Alignment Length:	407	Identity:	82/407 - (20%)
Similarity:	127/407 - (31%)	Gaps:	138/407 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   293 KVERFEMAVQTGDDLDINDSKAFEIAWLDNSSSLHTTRAVAKNALIFESEAVAMVPSGNCRVCDY 357
            ::|..|:....|....:..:|.|   |.  :..:...||.  :|::|:|    :|..    ||..
Human     5 RMENVEVFTAEGKGRGLKATKEF---WA--ADIIFAERAY--SAVVFDS----LVNF----VCHT 54

  Fly   358 CGITQFIPFPCIYCSNRLVVYCSRQCRFKHAAIHAVECFGHQIELFESFGEVFGMP-RLLQLAFR 421
            |...|.....|..|  :...||.|.|:......|..||     ...:.:|:|   | ..::||.|
Human    55 CFKRQEKLHRCGQC--KFAHYCDRTCQKDAWLNHKNEC-----SAIKRYGKV---PNENIRLAAR 109

  Fly   422 MLI------TGLPELLGHCRKKPTLSKLWSAINGGLQERQDIAYSAVLRLERLKEERPTDTVIAL 480
            ::.      |||.|                   |.|....|:..    .:|...||...|..:.:
Human   110 IMWRVEREGTGLTE-------------------GCLVSVDDLQN----HVEHFGEEEQKDLRVDV 151

  Fly   481 ALAAHILSIYLSKCTTFFDQLEKSLPTASRMSSAEWELLCAALLMRHI-GQLRHRSLTACRSFVL 544
                              |...:..|..|:..|.::        :.|| |.:.      |..|.|
Human   152 ------------------DTFLQYWPPQSQQFSMQY--------ISHIFGVIN------CNGFTL 184

  Fly   545 PADPHVFSPLNEFQLWAAPMRLQEGHLHLLAGEVAVVSYSVYPDTLNLCRHSCSSTICAKFSGRT 609
             :|                   |.|        :..|...::|: |.|..|.|.......|:...
Human   185 -SD-------------------QRG--------LQAVGVGIFPN-LGLVNHDCWPNCTVIFNNGN 220

  Fly   610 VTAL-------------ALLDLPAGSGIYNCFAGGNFQQLPREERTKQLLES-GIRCHCNACQLT 660
            ..|:             ||..:..|..:...:.  :|..: .|||.:||.:. ...|.|..||..
Human   221 HEAVKSMFHTQMRIELRALGKISEGEELTVSYI--DFLNV-SEERKRQLKKQYYFDCTCEHCQKK 282

  Fly   661 HSDDQFHKFHRYRCDNP 677
            ..||.|....    |||
Human   283 LKDDLFLGVK----DNP 295

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.