Protein Alignment dao and SMYD5

DIOPT Version :10

• Sequence 1: NP_609742.1
• Gene: dao / 34891
• FlyBaseID: FBgn0028862
• Length: 882
• Species: Drosophila melanogaster
• Sequence 2: NP_006053.2
• Gene: SMYD5 / 10322
• HGNCID: 16258
• Length: 418
• Species: Homo sapiens
• Alignment Length: 487
• Identity: 95/487 - (19%)
• Similarity: 143/487 - (29%)
• Gaps: 207/487 - (42%)

  Fly   316 EIAWLDNS--SSLHTTRAVAKNALIF-ESEAVAMVPSGNC----RVCDYC------------GIT 361
            |:.::.::  ..|..|:.:.|...|| |...||.....|.    |.||:|            .:|
Human    24 EVRFVSSAKGKGLFATQLIRKGETIFVERPLVAAQFLWNALYRYRACDHCLRALEKAEENAQRLT 88

  Fly   362 ----QFIPFP------------CIYCSNRLVVYCSRQCRFKHAA---IHAVECFG-------HQI 400
                |.:|.|            |.:|.   |:|||.:||.  ||   .|.|.|.|       |.:
Human    89 GKPGQVLPHPELCTVRKDLHQNCPHCQ---VMYCSAECRL--AATEQYHQVLCPGPSQDDPLHPL 148

  Fly   401 -ELFESFGEVFGMPRLLQLAFRMLITGLPELLGHCRKKPTLSKLWSAI-NGGLQERQDIAYSAV- 462
             :|.|::..:...|   :.|..||:..:...:...:.|....:|:|.. |....|.::|.:..:
Human   149 NKLQEAWRSIHYPP---ETASIMLMARMVATVKQAKDKDRWIRLFSQFCNKTANEEEEIVHKLLG 210

  Fly   463 ------------LRLERLKEERPTD--------TVIAL------ALAAHILSIYLSKCTT----- 496
                        |..|.|.||..:.        ::.||      .:....||.::..|.|
Human   211 DKFKGQLELLRRLFTEALYEEAVSQWFTPDGFRSLFALVGTNGQGIGTSSLSQWVHACDTLELKP 275

  Fly   497 --------FFDQLEKSLPTASRMSSAEWELLCAALLMRHIGQLRHRSLTACRSFVLPADPHVFSP 553
                    |.|||.|.:..|:
Human   276 QDREQLDAFIDQLYKDIEAAT-------------------------------------------- 296

  Fly   554 LNEFQLWAAPMRLQEGHLHLLAGEVAVVSYSVYPDTLNLCRHSCSSTICAKFSGRT----VTALA 614
             .||      :..:...|.:|.               :.|.|||.......|....    ||||.
Human   297 -GEF------LNCEGSGLFVLQ---------------SCCNHSCVPNAETSFPENNFLLHVTALE 339

  Fly   615 LLDLPAGSGIYNCFAGGNFQQLPREERTKQLLESGIRCHCNACQLTHSDDQFHKFHR----YRCD 675
              |:..|..|  |.:                       :.:.||...|....||..|    :.|.
Human   340 --DIKPGEEI--CIS-----------------------YLDCCQRERSRHSRHKILRENYLFVCS 377

  Fly   676 NPNCM-EIFTPNALPHAPSLRWWLSEEYTQPE 706
            .|.|: |...||.          .|||..:.|
Human   378 CPKCLAEADEPNV----------TSEEEEEEE 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dao	NP_609742.1	TPR repeat	200..235	CDD:276809
		TPR repeat	243..270	CDD:276809
		SET	<459..657	CDD:394802	34/241 (14%)
SMYD5	NP_006053.2	SET_SMYD5	22..384	CDD:380919	88/460 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	385..418		6/25 (24%)