Protein Alignment ZnT35C and SLC30A5

DIOPT Version :9

• Sequence 1: NP_609741.3
• Gene: ZnT35C / 34890
• FlyBaseID: FBgn0028516
• Length: 472
• Species: Drosophila melanogaster
• Sequence 2: NP_075053.2
• Gene: SLC30A5 / 64924
• HGNCID: 19089
• Length: 765
• Species: Homo sapiens
• Alignment Length: 409
• Identity: 100/409 - (24%)
• Similarity: 170/409 - (41%)
• Gaps: 97/409 - (23%)

  Fly    89 RKLIIASILCLVFMIAEIVGGVLSNSLAIATDAAHLLTDFASFMISLFAIWIAGRPSTQRMSFGW 153
            |::.....|.|:|...|:..|||:|||.:.:|..|:|.|.::.::.|||..::...:|:..|:|:
Human   417 RQIFYFLCLNLLFTFVELFYGVLTNSLGLISDGFHMLFDCSALVMGLFAALMSRWKATRIFSYGY 481

  Fly   154 YRAEVIGAMASVFMIWVITGILVWLAIGRLISGDYEVNAKIMLITSGLAILVNVIMGVQLQHGHS 218
            .|.|::....:...:.||...:...::.|||... |::..::...|...::||:|......|.||
Human   482 GRIEILSGFINGLFLIVIAFFVFMESVARLIDPP-ELDTHMLTPVSVGGLIVNLIGICAFSHAHS 545

  Fly   219 HGLGGGHGHSHGGSKNASHVQATSTPCSDSPSQRIEGGVAYAPEDAELPGGGLPTFSYQNTKLVD 283
            |    .||.|.|...::.|          |.|..:.|...:        |.|
Human   546 H----AHGASQGSCHSSDH----------SHSHHMHGHSDH--------GHG------------- 575

  Fly   284 PTLDLEIAAVLAETAPGSHHHGGPVGREAVNMNVRAALIHVIGDVIQSVGVFVAAGVI--YFWPE 346
                              |.||...|  .:|.|:|...:||:.|.:.|:||.|:..:|  :.|
Human   576 ------------------HSHGSAGG--GMNANMRGVFLHVLADTLGSIGVIVSTVLIEQFGW-- 618

  Fly   347 YSIVDPICTFVFSIIVLFTTFTIMKDAL-LVLMEGTPNY---MHYAEVLQIFQGIEGVERVHNLR 407
             .|.||:|:...:|::..:...::|||. ::|:...|.|   :|.|  |:..|.|||:....:..
Human   619 -FIADPLCSLFIAILIFLSVVPLIKDACQVLLLRLPPEYEKELHIA--LEKIQKIEGLISYRDPH 680

  Fly   408 IWALSINKVALSAHLAIAENANPKRILDAAT-----SAVHLRYNFFETTIQIED----------- 456
            .|..|.:.||.:.|:.:..:...:||:...|     :.|:      ..|||:|.
Human   681 FWRHSASIVAGTIHIQVTSDVLEQRIVQQVTGILKDAGVN------NLTIQVEKEAYFQHMSGLS 739

  Fly   457 --------YTAQMESCLQC 467
                    .|.||||...|
Human   740 TGFHDVLAMTKQMESMKYC 758

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZnT35C	NP_609741.3	CDF	100..457	CDD:273544	91/386 (24%)
		Cation_efflux	100..378	CDD:279834	68/280 (24%)
SLC30A5	NP_075053.2	CDF	428..729	CDD:273544	91/367 (25%)
		Cation_efflux	428..649	CDD:279834	68/279 (24%)
		His-rich loop	542..578		15/88 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	551..581		11/78 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1230
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810