Protein Alignment ZnT35C and SLC30A6

DIOPT Version :9

• Sequence 1: NP_609741.3
• Gene: ZnT35C / 34890
• FlyBaseID: FBgn0028516
• Length: 472
• Species: Drosophila melanogaster
• Sequence 2: NP_001180442.1
• Gene: SLC30A6 / 55676
• HGNCID: 19305
• Length: 501
• Species: Homo sapiens
• Alignment Length: 352
• Identity: 65/352 - (18%)
• Similarity: 128/352 - (36%)
• Gaps: 98/352 - (27%)

  Fly   111 LSNSLAIATDAAHLLTDFASFMISLFAIWIAGRPSTQRMSFGWYRAEVIGAMASVFMIWVITGIL 175
            |||||                |..|.:.|:..|..:...|||:.|.||:...||..:..:....:
Human   110 LSNSL----------------MTCLISYWVTLRKPSPVYSFGFERLEVLAVFASTVLAQLGALFI 158

  Fly   176 VWLAIGRLISGDYEVNAKIMLITSGLAILVNVIMGVQLQHGHSHGLGGGHGHSHGGSKNASHV-Q 239
            :..:..|.:. ..|::...:|:.:.:|:..|:...:.::                 :|..::| :
Human   159 LKESAERFLE-QPEIHTGRLLVGTFVALCFNLFTMLSIR-----------------NKPFAYVSE 205

  Fly   240 ATSTPCSDSPSQRIEGGVAYAPED-AELPG---GGLPTFSYQNTKLVDPTLDLEIAAVLAETAPG 300
            |.||              ::..|. |:|..   |.:|..|......::|.:.:::|...|
Human   206 AAST--------------SWLQEHVADLSRSLCGIIPGLSSIFLPRMNPFVLIDLAGAFA----- 251

  Fly   301 SHHHGGPVGREAVNMNVRAALIHVIGDVIQSVGVFVAAGVIYFWPEYSIVDPICTFVFSIIVLFT 365
                          :.:...||.:                    ..|..||.......:::...|
Human   252 --------------LCITYMLIEI--------------------NNYFAVDTASAIAIALMTFGT 282

  Fly   366 TFTIMKDALLVLMEGTPNYM--HYAEVLQIFQGIEGVERVHNLRIWALSINKVALSAHLAIAENA 428
            .:.:...:..||::.||.::  ...::::....::||..|.|...|.|....:|.|.|:.|..:|
Human   283 MYPMSVYSGKVLLQTTPPHVIGQLDKLIREVSTLDGVLEVRNEHFWTLGFGSLAGSVHVRIRRDA 347

  Fly   429 NPKRILDAATSAVHLRYNFFET-TIQI 454
            |.:.:|...|:.:   |....| |:||
Human   348 NEQMVLAHVTNRL---YTLVSTLTVQI 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZnT35C	NP_609741.3	CDF	100..457	CDD:273544	65/352 (18%)
		Cation_efflux	100..378	CDD:279834	43/271 (16%)
SLC30A6	NP_001180442.1	CzcD	<113..371	CDD:224151	60/347 (17%)
		Cation_efflux	113..295	CDD:279834	40/268 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1230
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810